Cargando…
Exposure to valproic acid (VPA) reproduces hdac1 loss of function phenotypes in zebrafish
Histone deacetylases are enzymes that remove acetyl groups from histone tails and are understood to act as repressors of transcriptional activity. Hdac1 has been previously shown to function in eye, pectoral fin, heart, liver, and pharyngeal skeletal development. We show that high doses of Valproic...
Autores principales: | Jones, Alec A., Willoner Jr., Terence, Mishoe Hernandez, Lacie, DeLaurier, April |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Caltech Library
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565572/ https://www.ncbi.nlm.nih.gov/pubmed/37829572 http://dx.doi.org/10.17912/micropub.biology.000908 |
Ejemplares similares
-
Codon optimized Tol2 transposase results in increased transient expression of a crystallin-GFP transgene in zebrafish
por: Mackey, Allison S., et al.
Publicado: (2020) -
A single copy transgenic mutant FUS strain reproduces age-dependent ALS phenotypes in C. elegans
por: Labarre, Audrey, et al.
Publicado: (2021) -
Blocking Wallerian degeneration by loss of Sarm1 does not promote axon resealing in zebrafish
por: Tian, Weili, et al.
Publicado: (2020) -
hdac4 mediates perichondral ossification and pharyngeal skeleton development in the zebrafish
por: DeLaurier, April, et al.
Publicado: (2019) -
Mob4 is required for neurodevelopment in zebrafish
por: Florindo, Claudia, et al.
Publicado: (2023)