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Functional analysis reveals driver cooperativity and novel mechanisms in endometrial carcinogenesis

High‐risk endometrial cancer has poor prognosis and is increasing in incidence. However, understanding of the molecular mechanisms which drive this disease is limited. We used genetically engineered mouse models (GEMM) to determine the functional consequences of missense and loss of function mutatio...

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Detalles Bibliográficos
Autores principales: Brown, Matthew, Leon, Alicia, Kedzierska, Katarzyna, Moore, Charlotte, Belnoue‐Davis, Hayley L, Flach, Susanne, Lydon, John P, DeMayo, Francesco J, Lewis, Annabelle, Bosse, Tjalling, Tomlinson, Ian, Church, David N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565641/
https://www.ncbi.nlm.nih.gov/pubmed/37589076
http://dx.doi.org/10.15252/emmm.202217094