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SBDS(R126T) rescues survival of sbds(−/−) zebrafish in a dose-dependent manner independently of Tp53

Defects in ribosomal biogenesis profoundly affect organismal development and cellular function, and these ribosomopathies produce a variety of phenotypes. One ribosomopathy, Shwachman–Diamond syndrome (SDS) is characterized by neutropenia, pancreatic exocrine insufficiency, and skeletal anomalies. S...

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Detalles Bibliográficos
Autores principales:	Oyarbide, Usua, Shah, Arish N, Staton, Morgan, Snyderman, Matthew, Sapra, Adya, Calo, Eliezer, Corey, Seth J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565674/ https://www.ncbi.nlm.nih.gov/pubmed/37816584 http://dx.doi.org/10.26508/lsa.202201856

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