Cargando…

SBDS(R126T) rescues survival of sbds(−/−) zebrafish in a dose-dependent manner independently of Tp53

Defects in ribosomal biogenesis profoundly affect organismal development and cellular function, and these ribosomopathies produce a variety of phenotypes. One ribosomopathy, Shwachman–Diamond syndrome (SDS) is characterized by neutropenia, pancreatic exocrine insufficiency, and skeletal anomalies. S...

Descripción completa

Detalles Bibliográficos
Autores principales:	Oyarbide, Usua, Shah, Arish N, Staton, Morgan, Snyderman, Matthew, Sapra, Adya, Calo, Eliezer, Corey, Seth J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565674/ https://www.ncbi.nlm.nih.gov/pubmed/37816584 http://dx.doi.org/10.26508/lsa.202201856

Ejemplares similares

Loss of Sbds in zebrafish leads to neutropenia and pancreas and liver atrophy
por: Oyarbide, Usua, et al.
Publicado: (2020)

Dual regulation of p53 by the ribosome maturation factor SBDS
por: Hao, Qian, et al.
Publicado: (2020)

SBDS Expression and Localization at the Mitotic Spindle in Human Myeloid Progenitors
por: Orelio, Claudia, et al.
Publicado: (2009)

SPS Beam Dump System (SBDS) Commissioning After Relocation and Upgrade
por: Van Trappen, Pieter, et al.
Publicado: (2022)

Structural variation and missense mutation in SBDS associated with Shwachman-Diamond syndrome
por: Carvalho, Claudia M B, et al.
Publicado: (2014)

FCN3 inhibits the progression of hepatocellular carcinoma by suppressing SBDS-mediated blockade of the p53 pathway
por: Ma, Dong, et al.
Publicado: (2023)

Altered Intracellular Localization and Mobility of SBDS Protein upon Mutation in Shwachman-Diamond Syndrome
por: Orelio, Claudia, et al.
Publicado: (2011)

In Vivo Senescence in the Sbds-Deficient Murine Pancreas: Cell-Type Specific Consequences of Translation Insufficiency
por: Tourlakis, Marina E., et al.
Publicado: (2015)

Peering through zebrafish to understand inherited bone marrow failure syndromes
por: Oyarbide, Usua, et al.
Publicado: (2019)

Inducible Sbds deletion impairs bone marrow niche capacity to engraft donor bone marrow after transplantation
por: Zha, Ji, et al.
Publicado: (2022)

A Comparative Molecular Dynamics Study of Selected Point Mutations in the Shwachman–Bodian–Diamond Syndrome Protein SBDS
por: Spinetti, Elena, et al.
Publicado: (2022)

Two mutations in the SBDS gene reveal a diagnosis of Shwachman–Diamond syndrome in a patient with atypical symptoms
por: Spangenberg, María Noel, et al.
Publicado: (2022)

Improved detection of SBDS gene mutation by a new method of next-generation sequencing analysis based on the Chinese mutation spectrum
por: Wu, Dong, et al.
Publicado: (2022)

Counteracting the Common Shwachman–Diamond Syndrome-Causing SBDS c.258+2T>C Mutation by RNA Therapeutics and Base/Prime Editing
por: Peretto, Laura, et al.
Publicado: (2023)

Case Report: Heterozygous Germline Variant in EIF6 Additional to Biallelic SBDS Pathogenic Variants in a Patient With Ribosomopathy Shwachman–Diamond Syndrome
por: Taha, Ibrahim, et al.
Publicado: (2022)

SBDS-Deficient Cells Have an Altered Homeostatic Equilibrium due to Translational Inefficiency Which Explains their Reduced Fitness and Provides a Logical Framework for Intervention
por: Calamita, Piera, et al.
Publicado: (2017)

Shwachman–Bodian–Diamond syndrome (SBDS) protein deficiency impairs translation re-initiation from C/EBPα and C/EBPβ mRNAs
por: In, Kyungmin, et al.
Publicado: (2016)

Shwachman–Bodian–Diamond syndrome (SBDS) protein is a direct inhibitor of protein phosphatase 2A (PP2A) activity and overexpressed in acute myeloid leukaemia
por: Dun, Matthew D., et al.
Publicado: (2020)

Shwachman-Diamond syndromes: clinical, genetic, and biochemical insights from the rare variants
por: Kawashima, Nozomu, et al.
Publicado: (2023)

Sperm and northern bottlenose whale interactions with deep-water trawlers in the western North Atlantic
por: Oyarbide, Usua, et al.
Publicado: (2023)

brca2 and tp53 Collaborate in Tumorigenesis in Zebrafish
por: Shive, Heather R., et al.
Publicado: (2014)

Identification of compounds that rescue otic and myelination defects in the zebrafish adgrg6 (gpr126) mutant
por: Diamantopoulou, Elvira, et al.
Publicado: (2019)

Tp53 Suppression Promotes Cardiomyocyte Proliferation during Zebrafish Heart Regeneration
por: Shoffner, Adam, et al.
Publicado: (2020)

73565 Defining tp53 tumor suppressor functions in zebrafish embryonal rhabdomyosarcoma
por: Baxi, Kunal, et al.
Publicado: (2021)

PPA1 promotes NSCLC progression via a JNK- and TP53-dependent manner
por: Luo, Dehong, et al.
Publicado: (2019)

Mitigating the Risk of t-MNs Development: TP53 or Not TP53?
por: Tesio, Melania
Publicado: (2023)

The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis
por: Leroy, Bernard, et al.
Publicado: (2013)

Correction: PPA1 promotes NSCLC progression via a JNK- and TP53-dependent manner
por: Luo, Dehong, et al.
Publicado: (2019)

PFKFB4 Drives the Oncogenicity in TP53-Mutated Hepatocellular Carcinoma in a Phosphatase-Dependent Manner
por: Kam, Charles Shing, et al.
Publicado: (2023)

TP53 and TP53-associated genes are correlated with the prognosis of paediatric neuroblastoma
por: Wang, Haiwei, et al.
Publicado: (2022)

Sex Reversal in Zebrafish fancl Mutants Is Caused by Tp53-Mediated Germ Cell Apoptosis
por: Rodríguez-Marí, Adriana, et al.
Publicado: (2010)

Myc-Induced Liver Tumors in Transgenic Zebrafish Can Regress in tp53 Null Mutation
por: Sun, Lili, et al.
Publicado: (2015)

Cooperation between liver-specific mutations of pten and tp53 genetically induces hepatocarcinogenesis in zebrafish
por: Luo, Juanjuan, et al.
Publicado: (2021)

Optimisation of TP53 reporters by systematic dissection of synthetic TP53 response elements
por: Trauernicht, Max, et al.
Publicado: (2023)

The TP53 fertility network
por: Paskulin, Diego d’Avila, et al.
Publicado: (2012)

TP53: an oncogene in disguise
por: Soussi, T, et al.
Publicado: (2015)

TP53 in Myelodysplastic Syndromes
por: Jiang, Yan, et al.
Publicado: (2021)

tp53 deficiency causes a wide tumor spectrum and increases embryonal rhabdomyosarcoma metastasis in zebrafish
por: Ignatius, Myron S, et al.
Publicado: (2018)

Studies of TP53 haplotypes in relation to LOH and TP53 mutations in breast cancer patients
por: Langerød, A, et al.
Publicado: (2000)

Expression signature based on TP53 target genes doesn't predict response to TP53-MDM2 inhibitor in wild type TP53 tumors
por: Sonkin, Dmitriy
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_av4edev72s6f0ql31mtcr0cf0s