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Fibrin microthrombi in bladder urothelium after SARS-CoV-2 infection: Case report
A 45-year-old male with diabetes, hypertension and hyperlipidemia was referred to urology due to persistent symptoms of urinary frequency, urgency, nocturia, erectile dysfunction, and constant pain localized to the bladder, pelvis, and perineal area, 3–4 months after SARS-CoV-2 infection. A bladder...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565678/ https://www.ncbi.nlm.nih.gov/pubmed/37829494 http://dx.doi.org/10.1016/j.eucr.2023.102575 |
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author | Hoang Roberts, Ly Zwaans, Bernadette M.M. Jabbar, Kausar Bartolone, Sarah N. Padmanabhan, Priya Peters, Kenneth M. |
author_facet | Hoang Roberts, Ly Zwaans, Bernadette M.M. Jabbar, Kausar Bartolone, Sarah N. Padmanabhan, Priya Peters, Kenneth M. |
author_sort | Hoang Roberts, Ly |
collection | PubMed |
description | A 45-year-old male with diabetes, hypertension and hyperlipidemia was referred to urology due to persistent symptoms of urinary frequency, urgency, nocturia, erectile dysfunction, and constant pain localized to the bladder, pelvis, and perineal area, 3–4 months after SARS-CoV-2 infection. A bladder biopsy showed urothelial mucosa and submucosa with hemorrhage and fibrin microthrombi in blood vessels. Hydrodistention of the bladder and pelvic floor physical therapy resolved symptoms, though bladder and pain symptoms returned upon reinfection with SARS-CoV-2. Urinalysis revealed elevated urinary interleukin-8, which may indicate localized bladder inflammation. |
format | Online Article Text |
id | pubmed-10565678 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-105656782023-10-12 Fibrin microthrombi in bladder urothelium after SARS-CoV-2 infection: Case report Hoang Roberts, Ly Zwaans, Bernadette M.M. Jabbar, Kausar Bartolone, Sarah N. Padmanabhan, Priya Peters, Kenneth M. Urol Case Rep Inflammation and Infection A 45-year-old male with diabetes, hypertension and hyperlipidemia was referred to urology due to persistent symptoms of urinary frequency, urgency, nocturia, erectile dysfunction, and constant pain localized to the bladder, pelvis, and perineal area, 3–4 months after SARS-CoV-2 infection. A bladder biopsy showed urothelial mucosa and submucosa with hemorrhage and fibrin microthrombi in blood vessels. Hydrodistention of the bladder and pelvic floor physical therapy resolved symptoms, though bladder and pain symptoms returned upon reinfection with SARS-CoV-2. Urinalysis revealed elevated urinary interleukin-8, which may indicate localized bladder inflammation. Elsevier 2023-09-25 /pmc/articles/PMC10565678/ /pubmed/37829494 http://dx.doi.org/10.1016/j.eucr.2023.102575 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Inflammation and Infection Hoang Roberts, Ly Zwaans, Bernadette M.M. Jabbar, Kausar Bartolone, Sarah N. Padmanabhan, Priya Peters, Kenneth M. Fibrin microthrombi in bladder urothelium after SARS-CoV-2 infection: Case report |
title | Fibrin microthrombi in bladder urothelium after SARS-CoV-2 infection: Case report |
title_full | Fibrin microthrombi in bladder urothelium after SARS-CoV-2 infection: Case report |
title_fullStr | Fibrin microthrombi in bladder urothelium after SARS-CoV-2 infection: Case report |
title_full_unstemmed | Fibrin microthrombi in bladder urothelium after SARS-CoV-2 infection: Case report |
title_short | Fibrin microthrombi in bladder urothelium after SARS-CoV-2 infection: Case report |
title_sort | fibrin microthrombi in bladder urothelium after sars-cov-2 infection: case report |
topic | Inflammation and Infection |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565678/ https://www.ncbi.nlm.nih.gov/pubmed/37829494 http://dx.doi.org/10.1016/j.eucr.2023.102575 |
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