Fibrin microthrombi in bladder urothelium after SARS-CoV-2 infection: Case report

A 45-year-old male with diabetes, hypertension and hyperlipidemia was referred to urology due to persistent symptoms of urinary frequency, urgency, nocturia, erectile dysfunction, and constant pain localized to the bladder, pelvis, and perineal area, 3–4 months after SARS-CoV-2 infection. A bladder...

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Detalles Bibliográficos
Autores principales: Hoang Roberts, Ly, Zwaans, Bernadette M.M., Jabbar, Kausar, Bartolone, Sarah N., Padmanabhan, Priya, Peters, Kenneth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Inflammation and Infection
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565678/
https://www.ncbi.nlm.nih.gov/pubmed/37829494
http://dx.doi.org/10.1016/j.eucr.2023.102575
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author Hoang Roberts, Ly
Zwaans, Bernadette M.M.
Jabbar, Kausar
Bartolone, Sarah N.
Padmanabhan, Priya
Peters, Kenneth M.
author_facet Hoang Roberts, Ly
Zwaans, Bernadette M.M.
Jabbar, Kausar
Bartolone, Sarah N.
Padmanabhan, Priya
Peters, Kenneth M.
author_sort Hoang Roberts, Ly
collection PubMed
description A 45-year-old male with diabetes, hypertension and hyperlipidemia was referred to urology due to persistent symptoms of urinary frequency, urgency, nocturia, erectile dysfunction, and constant pain localized to the bladder, pelvis, and perineal area, 3–4 months after SARS-CoV-2 infection. A bladder biopsy showed urothelial mucosa and submucosa with hemorrhage and fibrin microthrombi in blood vessels. Hydrodistention of the bladder and pelvic floor physical therapy resolved symptoms, though bladder and pain symptoms returned upon reinfection with SARS-CoV-2. Urinalysis revealed elevated urinary interleukin-8, which may indicate localized bladder inflammation.
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spelling pubmed-105656782023-10-12 Fibrin microthrombi in bladder urothelium after SARS-CoV-2 infection: Case report Hoang Roberts, Ly Zwaans, Bernadette M.M. Jabbar, Kausar Bartolone, Sarah N. Padmanabhan, Priya Peters, Kenneth M. Urol Case Rep Inflammation and Infection A 45-year-old male with diabetes, hypertension and hyperlipidemia was referred to urology due to persistent symptoms of urinary frequency, urgency, nocturia, erectile dysfunction, and constant pain localized to the bladder, pelvis, and perineal area, 3–4 months after SARS-CoV-2 infection. A bladder biopsy showed urothelial mucosa and submucosa with hemorrhage and fibrin microthrombi in blood vessels. Hydrodistention of the bladder and pelvic floor physical therapy resolved symptoms, though bladder and pain symptoms returned upon reinfection with SARS-CoV-2. Urinalysis revealed elevated urinary interleukin-8, which may indicate localized bladder inflammation. Elsevier 2023-09-25 /pmc/articles/PMC10565678/ /pubmed/37829494 http://dx.doi.org/10.1016/j.eucr.2023.102575 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Inflammation and Infection
Hoang Roberts, Ly
Zwaans, Bernadette M.M.
Jabbar, Kausar
Bartolone, Sarah N.
Padmanabhan, Priya
Peters, Kenneth M.
Fibrin microthrombi in bladder urothelium after SARS-CoV-2 infection: Case report
title Fibrin microthrombi in bladder urothelium after SARS-CoV-2 infection: Case report
title_full Fibrin microthrombi in bladder urothelium after SARS-CoV-2 infection: Case report
title_fullStr Fibrin microthrombi in bladder urothelium after SARS-CoV-2 infection: Case report
title_full_unstemmed Fibrin microthrombi in bladder urothelium after SARS-CoV-2 infection: Case report
title_short Fibrin microthrombi in bladder urothelium after SARS-CoV-2 infection: Case report
title_sort fibrin microthrombi in bladder urothelium after sars-cov-2 infection: case report
topic Inflammation and Infection
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565678/
https://www.ncbi.nlm.nih.gov/pubmed/37829494
http://dx.doi.org/10.1016/j.eucr.2023.102575
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