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Biochemical and X-ray analyses of the players involved in the faRel2/aTfaRel2 toxin–antitoxin operon

The aTfaRel2/faRel2 operon from Coprobacillus sp. D7 encodes a bicistronic type II toxin–antitoxin (TA) module. The FaRel2 toxin is a toxic small alarmone synthetase (toxSAS) that inhibits translation through the pyrophosphorylation of uncharged tRNAs at the 3′-CCA end. The toxin is neutralized by t...

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Detalles Bibliográficos
Autores principales: Dominguez-Molina, Lucia, Talavera, Ariel, Cepauskas, Albinas, Kurata, Tatsuaki, Echemendia-Blanco, Dannele, Hauryliuk, Vasili, Garcia-Pino, Abel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565793/
https://www.ncbi.nlm.nih.gov/pubmed/37728608
http://dx.doi.org/10.1107/S2053230X23007288