Clinical trial simulation to evaluate tenofovir disoproxil fumarate/emtricitabine HIV pre-exposure prophylaxis dosing during pregnancy

OBJECTIVE: To evaluate upward-adjustment of tenofovir disoproxil fumarate (TDF)/emtricitabine (FTC) pre-exposure prophylaxis (PrEP) dosing during pregnancy in order to maintain target plasma concentrations associated with HIV protection. DESIGN: Population pharmacokinetic (PK) modeling and clinical...

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Detalles Bibliográficos
Autores principales: Scott, Rachel K., Yu, Yifan, Marzinke, Mark A., Coleman, Jenell S., Hendrix, Craig W., Bies, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Reproductive Health
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565828/
https://www.ncbi.nlm.nih.gov/pubmed/37830105
http://dx.doi.org/10.3389/frph.2023.1224580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565828/
https://www.ncbi.nlm.nih.gov/pubmed/37830105
http://dx.doi.org/10.3389/frph.2023.1224580

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