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Circadian rhythm disorders in patients with advanced cancer: a scoping review

Circadian rhythms can be demonstrated in several biomarkers and behavioural activities, with rhythmical patterns occurring roughly over a 24-h period. Circadian disorders occur in patients with cancer and may be associated with poor clinical outcomes. This scoping review aimed to identify circadian...

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Autores principales: Gouldthorpe, Craig, Power, Jenny, Davies, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565850/
https://www.ncbi.nlm.nih.gov/pubmed/37829342
http://dx.doi.org/10.3389/fonc.2023.1240284
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author Gouldthorpe, Craig
Power, Jenny
Davies, Andrew
author_facet Gouldthorpe, Craig
Power, Jenny
Davies, Andrew
author_sort Gouldthorpe, Craig
collection PubMed
description Circadian rhythms can be demonstrated in several biomarkers and behavioural activities, with rhythmical patterns occurring roughly over a 24-h period. Circadian disorders occur in patients with cancer and may be associated with poor clinical outcomes. This scoping review aimed to identify circadian rhythm research and reporting practices, circadian rhythm patterns, circadian rhythm disorders, and relevant associations of circadian rhythm disorders in patients with advanced cancer. Studies involved adult patients with locally advanced or metastatic cancer and used objective measures of circadian rhythmicity. Two independent authors completed initial screening of title and abstracts, full text reviews, data extraction, and data checking. A total of 98 articles were highlighted in the scoping review, which utilised physical activity measures (actigraphy and polysomnography), biomarkers (cortisol and melatonin), or a combination. Several circadian rhythms are commonly disordered amongst patients with advanced cancer and have significant implications for symptom burden, quality of life, and survival. It remains unclear which patients are most at risk of a circadian rhythm disorder. Significant heterogeneity exists in research and reporting practices. Standardising this approach may address discrepancies in the current literature and allow for research to focus on the most relevant parameters and approaches to improving circadian rhythmicity.
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spelling pubmed-105658502023-10-12 Circadian rhythm disorders in patients with advanced cancer: a scoping review Gouldthorpe, Craig Power, Jenny Davies, Andrew Front Oncol Oncology Circadian rhythms can be demonstrated in several biomarkers and behavioural activities, with rhythmical patterns occurring roughly over a 24-h period. Circadian disorders occur in patients with cancer and may be associated with poor clinical outcomes. This scoping review aimed to identify circadian rhythm research and reporting practices, circadian rhythm patterns, circadian rhythm disorders, and relevant associations of circadian rhythm disorders in patients with advanced cancer. Studies involved adult patients with locally advanced or metastatic cancer and used objective measures of circadian rhythmicity. Two independent authors completed initial screening of title and abstracts, full text reviews, data extraction, and data checking. A total of 98 articles were highlighted in the scoping review, which utilised physical activity measures (actigraphy and polysomnography), biomarkers (cortisol and melatonin), or a combination. Several circadian rhythms are commonly disordered amongst patients with advanced cancer and have significant implications for symptom burden, quality of life, and survival. It remains unclear which patients are most at risk of a circadian rhythm disorder. Significant heterogeneity exists in research and reporting practices. Standardising this approach may address discrepancies in the current literature and allow for research to focus on the most relevant parameters and approaches to improving circadian rhythmicity. Frontiers Media S.A. 2023-09-26 /pmc/articles/PMC10565850/ /pubmed/37829342 http://dx.doi.org/10.3389/fonc.2023.1240284 Text en Copyright © 2023 Gouldthorpe, Power and Davies https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Gouldthorpe, Craig
Power, Jenny
Davies, Andrew
Circadian rhythm disorders in patients with advanced cancer: a scoping review
title Circadian rhythm disorders in patients with advanced cancer: a scoping review
title_full Circadian rhythm disorders in patients with advanced cancer: a scoping review
title_fullStr Circadian rhythm disorders in patients with advanced cancer: a scoping review
title_full_unstemmed Circadian rhythm disorders in patients with advanced cancer: a scoping review
title_short Circadian rhythm disorders in patients with advanced cancer: a scoping review
title_sort circadian rhythm disorders in patients with advanced cancer: a scoping review
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565850/
https://www.ncbi.nlm.nih.gov/pubmed/37829342
http://dx.doi.org/10.3389/fonc.2023.1240284
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