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Red and processed meat and pancreatic cancer risk: a meta-analysis
BACKGROUND: The relationship between red and processed meat consumption and pancreatic cancer risk is controversial and no study has looked specifically at the correlation for 6 years. We conducted a meta-analysis to summarize the evidence about the association between them. METHODS: We systematical...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565855/ https://www.ncbi.nlm.nih.gov/pubmed/37829734 http://dx.doi.org/10.3389/fnut.2023.1249407 |
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author | Sun, Yudi He, Xinyi Sun, Yan |
author_facet | Sun, Yudi He, Xinyi Sun, Yan |
author_sort | Sun, Yudi |
collection | PubMed |
description | BACKGROUND: The relationship between red and processed meat consumption and pancreatic cancer risk is controversial and no study has looked specifically at the correlation for 6 years. We conducted a meta-analysis to summarize the evidence about the association between them. METHODS: We systematically searched PubMed, Embase and Cochrane Library for studies of red or processed meat consumption and pancreatic cancer published from December 2016 to July 2022. We performed random-effects models to pool the relative risks from individual studies. Subgroup analyses were used to figure out heterogeneity. We also performed publication bias analysis. RESULTS: Seven cohort studies and one case–control study that contained a total of 7,158 pancreatic cancer cases from 805,177 participants were eligible for inclusion. The combined RRs (95% CI) comparing highest and lowest categories were 1.07 (95% CI: 0.91–1.26; p = 0.064) for red meat and 1.04 (95% CI: 0.81–1.33; p = 0.006) for processed meat with statistically significant heterogeneity. CONCLUSION: This meta-analysis suggested that red and processed meat consumption has no relationship with pancreatic cancer risk. |
format | Online Article Text |
id | pubmed-10565855 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-105658552023-10-12 Red and processed meat and pancreatic cancer risk: a meta-analysis Sun, Yudi He, Xinyi Sun, Yan Front Nutr Nutrition BACKGROUND: The relationship between red and processed meat consumption and pancreatic cancer risk is controversial and no study has looked specifically at the correlation for 6 years. We conducted a meta-analysis to summarize the evidence about the association between them. METHODS: We systematically searched PubMed, Embase and Cochrane Library for studies of red or processed meat consumption and pancreatic cancer published from December 2016 to July 2022. We performed random-effects models to pool the relative risks from individual studies. Subgroup analyses were used to figure out heterogeneity. We also performed publication bias analysis. RESULTS: Seven cohort studies and one case–control study that contained a total of 7,158 pancreatic cancer cases from 805,177 participants were eligible for inclusion. The combined RRs (95% CI) comparing highest and lowest categories were 1.07 (95% CI: 0.91–1.26; p = 0.064) for red meat and 1.04 (95% CI: 0.81–1.33; p = 0.006) for processed meat with statistically significant heterogeneity. CONCLUSION: This meta-analysis suggested that red and processed meat consumption has no relationship with pancreatic cancer risk. Frontiers Media S.A. 2023-09-27 /pmc/articles/PMC10565855/ /pubmed/37829734 http://dx.doi.org/10.3389/fnut.2023.1249407 Text en Copyright © 2023 Sun, He and Sun. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Nutrition Sun, Yudi He, Xinyi Sun, Yan Red and processed meat and pancreatic cancer risk: a meta-analysis |
title | Red and processed meat and pancreatic cancer risk: a meta-analysis |
title_full | Red and processed meat and pancreatic cancer risk: a meta-analysis |
title_fullStr | Red and processed meat and pancreatic cancer risk: a meta-analysis |
title_full_unstemmed | Red and processed meat and pancreatic cancer risk: a meta-analysis |
title_short | Red and processed meat and pancreatic cancer risk: a meta-analysis |
title_sort | red and processed meat and pancreatic cancer risk: a meta-analysis |
topic | Nutrition |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565855/ https://www.ncbi.nlm.nih.gov/pubmed/37829734 http://dx.doi.org/10.3389/fnut.2023.1249407 |
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