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Red and processed meat and pancreatic cancer risk: a meta-analysis

BACKGROUND: The relationship between red and processed meat consumption and pancreatic cancer risk is controversial and no study has looked specifically at the correlation for 6 years. We conducted a meta-analysis to summarize the evidence about the association between them. METHODS: We systematical...

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Autores principales: Sun, Yudi, He, Xinyi, Sun, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565855/
https://www.ncbi.nlm.nih.gov/pubmed/37829734
http://dx.doi.org/10.3389/fnut.2023.1249407
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author Sun, Yudi
He, Xinyi
Sun, Yan
author_facet Sun, Yudi
He, Xinyi
Sun, Yan
author_sort Sun, Yudi
collection PubMed
description BACKGROUND: The relationship between red and processed meat consumption and pancreatic cancer risk is controversial and no study has looked specifically at the correlation for 6 years. We conducted a meta-analysis to summarize the evidence about the association between them. METHODS: We systematically searched PubMed, Embase and Cochrane Library for studies of red or processed meat consumption and pancreatic cancer published from December 2016 to July 2022. We performed random-effects models to pool the relative risks from individual studies. Subgroup analyses were used to figure out heterogeneity. We also performed publication bias analysis. RESULTS: Seven cohort studies and one case–control study that contained a total of 7,158 pancreatic cancer cases from 805,177 participants were eligible for inclusion. The combined RRs (95% CI) comparing highest and lowest categories were 1.07 (95% CI: 0.91–1.26; p = 0.064) for red meat and 1.04 (95% CI: 0.81–1.33; p = 0.006) for processed meat with statistically significant heterogeneity. CONCLUSION: This meta-analysis suggested that red and processed meat consumption has no relationship with pancreatic cancer risk.
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spelling pubmed-105658552023-10-12 Red and processed meat and pancreatic cancer risk: a meta-analysis Sun, Yudi He, Xinyi Sun, Yan Front Nutr Nutrition BACKGROUND: The relationship between red and processed meat consumption and pancreatic cancer risk is controversial and no study has looked specifically at the correlation for 6 years. We conducted a meta-analysis to summarize the evidence about the association between them. METHODS: We systematically searched PubMed, Embase and Cochrane Library for studies of red or processed meat consumption and pancreatic cancer published from December 2016 to July 2022. We performed random-effects models to pool the relative risks from individual studies. Subgroup analyses were used to figure out heterogeneity. We also performed publication bias analysis. RESULTS: Seven cohort studies and one case–control study that contained a total of 7,158 pancreatic cancer cases from 805,177 participants were eligible for inclusion. The combined RRs (95% CI) comparing highest and lowest categories were 1.07 (95% CI: 0.91–1.26; p = 0.064) for red meat and 1.04 (95% CI: 0.81–1.33; p = 0.006) for processed meat with statistically significant heterogeneity. CONCLUSION: This meta-analysis suggested that red and processed meat consumption has no relationship with pancreatic cancer risk. Frontiers Media S.A. 2023-09-27 /pmc/articles/PMC10565855/ /pubmed/37829734 http://dx.doi.org/10.3389/fnut.2023.1249407 Text en Copyright © 2023 Sun, He and Sun. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Nutrition
Sun, Yudi
He, Xinyi
Sun, Yan
Red and processed meat and pancreatic cancer risk: a meta-analysis
title Red and processed meat and pancreatic cancer risk: a meta-analysis
title_full Red and processed meat and pancreatic cancer risk: a meta-analysis
title_fullStr Red and processed meat and pancreatic cancer risk: a meta-analysis
title_full_unstemmed Red and processed meat and pancreatic cancer risk: a meta-analysis
title_short Red and processed meat and pancreatic cancer risk: a meta-analysis
title_sort red and processed meat and pancreatic cancer risk: a meta-analysis
topic Nutrition
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10565855/
https://www.ncbi.nlm.nih.gov/pubmed/37829734
http://dx.doi.org/10.3389/fnut.2023.1249407
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