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Tampon Vital Pulp Therapy in the Management of Excessive Haemorrhage in Inflamed Pulps: A Hypothesis

Current principles in vital pulp therapy (VPT) modalities emphasise the importance of haemostasis and normal clotting in the achievement of successful treatment outcomes. However, the aforementioned notion could be challenged by the new and recent emerging evidence; suggesting that prolonged or exce...

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Autores principales: Ardavan, Ardavan, Roghanizadeh, Leyla, Asgary, Saeed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Center for Endodontic Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566001/
https://www.ncbi.nlm.nih.gov/pubmed/37829835
http://dx.doi.org/10.22037/iej.v18i4.43232
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author Ardavan, Ardavan
Roghanizadeh, Leyla
Asgary, Saeed
author_facet Ardavan, Ardavan
Roghanizadeh, Leyla
Asgary, Saeed
author_sort Ardavan, Ardavan
collection PubMed
description Current principles in vital pulp therapy (VPT) modalities emphasise the importance of haemostasis and normal clotting in the achievement of successful treatment outcomes. However, the aforementioned notion could be challenged by the new and recent emerging evidence; suggesting that prolonged or excessive bleeding/haemorrhage (PB) in cases of intensly inflamed pulps, conventionally infamous as irreversible pulpitis (IP), may not impede the healing potential of the remaining dental pulp tissue following VPTs using endodontic biomaterials. “Tampon VPT (tVPT)” may be considered a treatment approach for the management of stated IP cases; characterised by severe pulpal inflammation and delayed clotting process. The presented hypothesis evaluates clinical studies, experimental research and molecular impacts on clotting within the inflamed dental pulp, so as to explore the efficacy as well as the safety of tVPT as a viable treatment option. Latest clinical investigations have reported positive outcomes with tVPT; even in the presence of IP with PB. It has been shown that inflamed dental pulp tissues exhibit molecular impacts on the clotting cascade, which may contribute to the delayed clotting process. Nonetheless, the healing capacity of the dental pulp is not negatively affected by hyperaemia. Additionally, enhanced blood flow in the inflamed pulpal tissues may be associated with improved healing and boosted hard tissue formation. Moreover, tVPT could possibly promote pulpal healing and/or regeneration through continuing the presentation of essential nutrients, e.g. oxygen, and growth factors to the injured tissue. Furthermore, increased blood flow may facilitate the recruitment of immune and reparative cells; promoting tissue repair and encouraging the formation of dentinal bridge(s) after VPTs. Consequently, the state-of-the-art research and their findings could support the hypothesis that tVPT may effectively manage IP cases with PB and contribute to favourable outcomes.
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spelling pubmed-105660012023-10-12 Tampon Vital Pulp Therapy in the Management of Excessive Haemorrhage in Inflamed Pulps: A Hypothesis Ardavan, Ardavan Roghanizadeh, Leyla Asgary, Saeed Iran Endod J Hypothesis Current principles in vital pulp therapy (VPT) modalities emphasise the importance of haemostasis and normal clotting in the achievement of successful treatment outcomes. However, the aforementioned notion could be challenged by the new and recent emerging evidence; suggesting that prolonged or excessive bleeding/haemorrhage (PB) in cases of intensly inflamed pulps, conventionally infamous as irreversible pulpitis (IP), may not impede the healing potential of the remaining dental pulp tissue following VPTs using endodontic biomaterials. “Tampon VPT (tVPT)” may be considered a treatment approach for the management of stated IP cases; characterised by severe pulpal inflammation and delayed clotting process. The presented hypothesis evaluates clinical studies, experimental research and molecular impacts on clotting within the inflamed dental pulp, so as to explore the efficacy as well as the safety of tVPT as a viable treatment option. Latest clinical investigations have reported positive outcomes with tVPT; even in the presence of IP with PB. It has been shown that inflamed dental pulp tissues exhibit molecular impacts on the clotting cascade, which may contribute to the delayed clotting process. Nonetheless, the healing capacity of the dental pulp is not negatively affected by hyperaemia. Additionally, enhanced blood flow in the inflamed pulpal tissues may be associated with improved healing and boosted hard tissue formation. Moreover, tVPT could possibly promote pulpal healing and/or regeneration through continuing the presentation of essential nutrients, e.g. oxygen, and growth factors to the injured tissue. Furthermore, increased blood flow may facilitate the recruitment of immune and reparative cells; promoting tissue repair and encouraging the formation of dentinal bridge(s) after VPTs. Consequently, the state-of-the-art research and their findings could support the hypothesis that tVPT may effectively manage IP cases with PB and contribute to favourable outcomes. Iranian Center for Endodontic Research 2023 /pmc/articles/PMC10566001/ /pubmed/37829835 http://dx.doi.org/10.22037/iej.v18i4.43232 Text en https://creativecommons.org/licenses/by-nc-sa/4.0/This open-access article has been distributed under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0 https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Hypothesis
Ardavan, Ardavan
Roghanizadeh, Leyla
Asgary, Saeed
Tampon Vital Pulp Therapy in the Management of Excessive Haemorrhage in Inflamed Pulps: A Hypothesis
title Tampon Vital Pulp Therapy in the Management of Excessive Haemorrhage in Inflamed Pulps: A Hypothesis
title_full Tampon Vital Pulp Therapy in the Management of Excessive Haemorrhage in Inflamed Pulps: A Hypothesis
title_fullStr Tampon Vital Pulp Therapy in the Management of Excessive Haemorrhage in Inflamed Pulps: A Hypothesis
title_full_unstemmed Tampon Vital Pulp Therapy in the Management of Excessive Haemorrhage in Inflamed Pulps: A Hypothesis
title_short Tampon Vital Pulp Therapy in the Management of Excessive Haemorrhage in Inflamed Pulps: A Hypothesis
title_sort tampon vital pulp therapy in the management of excessive haemorrhage in inflamed pulps: a hypothesis
topic Hypothesis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566001/
https://www.ncbi.nlm.nih.gov/pubmed/37829835
http://dx.doi.org/10.22037/iej.v18i4.43232
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