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Genomic, transcriptomic and epigenomic sequencing data of the B-cell leukemia cell line REH

OBJECTIVES: The aim of this data paper is to describe a collection of 33 genomic, transcriptomic and epigenomic sequencing datasets of the B-cell acute lymphoblastic leukemia (ALL) cell line REH. REH is one of the most frequently used cell lines for functional studies of pediatric ALL, and these dat...

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Autores principales: Lysenkova Wiklander, Mariya, Övernäs, Elin, Lagensjö, Johanna, Raine, Amanda, Petri, Anna, Wiman, Ann-Christin, Ramsell, Jon, Marincevic-Zuniga, Yanara, Gezelius, Henrik, Martin, Tom, Bunikis, Ignas, Ekberg, Sara, Erlandsson, Rikard, Larsson, Pontus, Mosbech, Mai-Britt, Häggqvist, Susana, Hellstedt Kerje, Susanne, Feuk, Lars, Ameur, Adam, Liljedahl, Ulrika, Nordlund, Jessica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566058/
https://www.ncbi.nlm.nih.gov/pubmed/37817248
http://dx.doi.org/10.1186/s13104-023-06537-2
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author Lysenkova Wiklander, Mariya
Övernäs, Elin
Lagensjö, Johanna
Raine, Amanda
Petri, Anna
Wiman, Ann-Christin
Ramsell, Jon
Marincevic-Zuniga, Yanara
Gezelius, Henrik
Martin, Tom
Bunikis, Ignas
Ekberg, Sara
Erlandsson, Rikard
Larsson, Pontus
Mosbech, Mai-Britt
Häggqvist, Susana
Hellstedt Kerje, Susanne
Feuk, Lars
Ameur, Adam
Liljedahl, Ulrika
Nordlund, Jessica
author_facet Lysenkova Wiklander, Mariya
Övernäs, Elin
Lagensjö, Johanna
Raine, Amanda
Petri, Anna
Wiman, Ann-Christin
Ramsell, Jon
Marincevic-Zuniga, Yanara
Gezelius, Henrik
Martin, Tom
Bunikis, Ignas
Ekberg, Sara
Erlandsson, Rikard
Larsson, Pontus
Mosbech, Mai-Britt
Häggqvist, Susana
Hellstedt Kerje, Susanne
Feuk, Lars
Ameur, Adam
Liljedahl, Ulrika
Nordlund, Jessica
author_sort Lysenkova Wiklander, Mariya
collection PubMed
description OBJECTIVES: The aim of this data paper is to describe a collection of 33 genomic, transcriptomic and epigenomic sequencing datasets of the B-cell acute lymphoblastic leukemia (ALL) cell line REH. REH is one of the most frequently used cell lines for functional studies of pediatric ALL, and these data provide a multi-faceted characterization of its molecular features. The datasets described herein, generated with short- and long-read sequencing technologies, can both provide insights into the complex aberrant karyotype of REH, and be used as reference datasets for sequencing data quality assessment or for methods development. DATA DESCRIPTION: This paper describes 33 datasets corresponding to 867 gigabases of raw sequencing data generated from the REH cell line. These datasets include five different approaches for whole genome sequencing (WGS) on four sequencing platforms, two RNA sequencing (RNA-seq) techniques on two different sequencing platforms, DNA methylation sequencing, and single-cell ATAC-sequencing.
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spelling pubmed-105660582023-10-12 Genomic, transcriptomic and epigenomic sequencing data of the B-cell leukemia cell line REH Lysenkova Wiklander, Mariya Övernäs, Elin Lagensjö, Johanna Raine, Amanda Petri, Anna Wiman, Ann-Christin Ramsell, Jon Marincevic-Zuniga, Yanara Gezelius, Henrik Martin, Tom Bunikis, Ignas Ekberg, Sara Erlandsson, Rikard Larsson, Pontus Mosbech, Mai-Britt Häggqvist, Susana Hellstedt Kerje, Susanne Feuk, Lars Ameur, Adam Liljedahl, Ulrika Nordlund, Jessica BMC Res Notes Data Note OBJECTIVES: The aim of this data paper is to describe a collection of 33 genomic, transcriptomic and epigenomic sequencing datasets of the B-cell acute lymphoblastic leukemia (ALL) cell line REH. REH is one of the most frequently used cell lines for functional studies of pediatric ALL, and these data provide a multi-faceted characterization of its molecular features. The datasets described herein, generated with short- and long-read sequencing technologies, can both provide insights into the complex aberrant karyotype of REH, and be used as reference datasets for sequencing data quality assessment or for methods development. DATA DESCRIPTION: This paper describes 33 datasets corresponding to 867 gigabases of raw sequencing data generated from the REH cell line. These datasets include five different approaches for whole genome sequencing (WGS) on four sequencing platforms, two RNA sequencing (RNA-seq) techniques on two different sequencing platforms, DNA methylation sequencing, and single-cell ATAC-sequencing. BioMed Central 2023-10-10 /pmc/articles/PMC10566058/ /pubmed/37817248 http://dx.doi.org/10.1186/s13104-023-06537-2 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Data Note
Lysenkova Wiklander, Mariya
Övernäs, Elin
Lagensjö, Johanna
Raine, Amanda
Petri, Anna
Wiman, Ann-Christin
Ramsell, Jon
Marincevic-Zuniga, Yanara
Gezelius, Henrik
Martin, Tom
Bunikis, Ignas
Ekberg, Sara
Erlandsson, Rikard
Larsson, Pontus
Mosbech, Mai-Britt
Häggqvist, Susana
Hellstedt Kerje, Susanne
Feuk, Lars
Ameur, Adam
Liljedahl, Ulrika
Nordlund, Jessica
Genomic, transcriptomic and epigenomic sequencing data of the B-cell leukemia cell line REH
title Genomic, transcriptomic and epigenomic sequencing data of the B-cell leukemia cell line REH
title_full Genomic, transcriptomic and epigenomic sequencing data of the B-cell leukemia cell line REH
title_fullStr Genomic, transcriptomic and epigenomic sequencing data of the B-cell leukemia cell line REH
title_full_unstemmed Genomic, transcriptomic and epigenomic sequencing data of the B-cell leukemia cell line REH
title_short Genomic, transcriptomic and epigenomic sequencing data of the B-cell leukemia cell line REH
title_sort genomic, transcriptomic and epigenomic sequencing data of the b-cell leukemia cell line reh
topic Data Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566058/
https://www.ncbi.nlm.nih.gov/pubmed/37817248
http://dx.doi.org/10.1186/s13104-023-06537-2
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