Isoforskolin modulates AQP4-SPP1-PIK3C3 related pathway for chronic obstructive pulmonary disease via cAMP signaling

BACKGROUND: Cyclic adenosine monophosphate (cAMP) levels are directly activated by adenylate cyclase (AC) and play an anti-inflammatory role in chronic obstructive pulmonary disease (COPD). Previously, we have shown that isoforskolin (ISOF) can effectively activate AC1 and AC2 in vitro, improve pulm...

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Detalles Bibliográficos
Autores principales: Lin, Haochang, Cheng, Sha, Yang, Songye, Zhang, Qian, Wang, Lueli, Li, Jiangya, Zhang, Xinyue, Liang, Liju, Zhou, Xiaoqian, Yang, Furong, Song, Jingfeng, Cao, Xue, Yang, Weimin, Weng, Zhiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566078/
https://www.ncbi.nlm.nih.gov/pubmed/37817209
http://dx.doi.org/10.1186/s13020-023-00778-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566078/
https://www.ncbi.nlm.nih.gov/pubmed/37817209
http://dx.doi.org/10.1186/s13020-023-00778-w

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