Isoforskolin modulates AQP4-SPP1-PIK3C3 related pathway for chronic obstructive pulmonary disease via cAMP signaling

BACKGROUND: Cyclic adenosine monophosphate (cAMP) levels are directly activated by adenylate cyclase (AC) and play an anti-inflammatory role in chronic obstructive pulmonary disease (COPD). Previously, we have shown that isoforskolin (ISOF) can effectively activate AC1 and AC2 in vitro, improve pulm...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Haochang, Cheng, Sha, Yang, Songye, Zhang, Qian, Wang, Lueli, Li, Jiangya, Zhang, Xinyue, Liang, Liju, Zhou, Xiaoqian, Yang, Furong, Song, Jingfeng, Cao, Xue, Yang, Weimin, Weng, Zhiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566078/
https://www.ncbi.nlm.nih.gov/pubmed/37817209
http://dx.doi.org/10.1186/s13020-023-00778-w

Ejemplares similares

Ejemplares similares