Doxapram versus placebo in preterm newborns: a study protocol for an international double blinded multicentre randomized controlled trial (DOXA-trial)

BACKGROUND: Apnoea of prematurity (AOP) is one of the most common diagnoses among preterm infants. AOP often leads to hypoxemia and bradycardia which are associated with an increased risk of death or disability. In addition to caffeine therapy and non-invasive respiratory support, doxapram might be...

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Detalles Bibliográficos
Autores principales: Poppe, Jarinda A., Flint, Robert B., Smits, Anne, Willemsen, Sten P., Storm, Kelly K., Nuytemans, Debbie H., Onland, Wes, Poley, Marten J., de Boode, Willem P., Carkeek, Katherine, Cassart, Vincent, Cornette, Luc, Dijk, Peter H., Hemels, Marieke A. C., Hermans, Isabelle, Hütten, Matthias C., Kelen, Dorottya, de Kort, Ellen H. M., Kroon, André A., Lefevere, Julie, Plaskie, Katleen, Stewart, Breanne, Voeten, Michiel, van Weissenbruch, Mirjam M., Williams, Olivia, Zonnenberg, Inge A., Lacaze-Masmonteil, Thierry, Pas, Arjan B.te, Reiss, Irwin K. M., van Kaam, Anton H., Allegaert, Karel, Hutten, G. Jeroen, Simons, Sinno H. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566117/
https://www.ncbi.nlm.nih.gov/pubmed/37817255
http://dx.doi.org/10.1186/s13063-023-07683-5

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