Cargando…
Targeting CD22 for B-cell hematologic malignancies
CD19-targeted chimeric receptor antigen (CAR)-T cell therapy has shown remarkable clinical efficacy in the treatment of relapsed or refractory (R/R) B-cell malignancies. However, 30%–60% of patients eventually relapsed, with the CD19-negative relapse being an important hurdle to sustained remission....
Autores principales: | Xu, Jia, Luo, Wenjing, Li, Chenggong, Mei, Heng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566133/ https://www.ncbi.nlm.nih.gov/pubmed/37821931 http://dx.doi.org/10.1186/s40164-023-00454-7 |
Ejemplares similares
-
Targeting CD22 for the Treatment of B-Cell Malignancies
por: Shah, Nikesh N, et al.
Publicado: (2021) -
Adverse effects in hematologic malignancies treated with chimeric antigen receptor (CAR) T cell therapy: a systematic review and Meta-analysis
por: Luo, Wenjing, et al.
Publicado: (2022) -
CD123 as a Therapeutic Target in the Treatment of Hematological Malignancies
por: Testa, Ugo, et al.
Publicado: (2019) -
T Cell Exhaustion and CAR-T Immunotherapy in Hematological Malignancies
por: Tang, Lu, et al.
Publicado: (2021) -
IL-10 plus the EASIX score predict bleeding events after anti-CD19 CAR T-cell therapy
por: Wang, Xindi, et al.
Publicado: (2023)