A Case Report of Syphilis That Was Difficult to Distinguish From Penile Carcinoma

A 43-year-old man presented with penile induration and lymphadenopathy. Computed tomography revealed multiple enlarged lymph nodes (LNs). Penile cancer was suspected, and a LN biopsy was performed. Histopathological examination revealed inflammation and fibrosis, with no findings indicating malignan...

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Autores principales: Tomioka, Masayuki, Uno, Hiromi, Seike, Kensaku, Iinuma, Koji, Tatsuhiko, Miyazaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Urology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566309/
https://www.ncbi.nlm.nih.gov/pubmed/37829948
http://dx.doi.org/10.7759/cureus.45029
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author Tomioka, Masayuki
Uno, Hiromi
Seike, Kensaku
Iinuma, Koji
Tatsuhiko, Miyazaki
author_facet Tomioka, Masayuki
Uno, Hiromi
Seike, Kensaku
Iinuma, Koji
Tatsuhiko, Miyazaki
author_sort Tomioka, Masayuki
collection PubMed
description A 43-year-old man presented with penile induration and lymphadenopathy. Computed tomography revealed multiple enlarged lymph nodes (LNs). Penile cancer was suspected, and a LN biopsy was performed. Histopathological examination revealed inflammation and fibrosis, with no findings indicating malignancy. Serological examination confirmed syphilis and treatment with amoxicillin was initiated. Thereafter, swelling in the LNs improved quickly. Penile cancer is usually suspected in the presence of penile induration. However, syphilis can also present with similar symptoms. To distinguish between syphilis and penile cancer, the patient's history, results of physical examination, and presence of tumor and infectious markers should be considered.
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spelling pubmed-105663092023-10-12 A Case Report of Syphilis That Was Difficult to Distinguish From Penile Carcinoma Tomioka, Masayuki Uno, Hiromi Seike, Kensaku Iinuma, Koji Tatsuhiko, Miyazaki Cureus Urology A 43-year-old man presented with penile induration and lymphadenopathy. Computed tomography revealed multiple enlarged lymph nodes (LNs). Penile cancer was suspected, and a LN biopsy was performed. Histopathological examination revealed inflammation and fibrosis, with no findings indicating malignancy. Serological examination confirmed syphilis and treatment with amoxicillin was initiated. Thereafter, swelling in the LNs improved quickly. Penile cancer is usually suspected in the presence of penile induration. However, syphilis can also present with similar symptoms. To distinguish between syphilis and penile cancer, the patient's history, results of physical examination, and presence of tumor and infectious markers should be considered. Cureus 2023-09-11 /pmc/articles/PMC10566309/ /pubmed/37829948 http://dx.doi.org/10.7759/cureus.45029 Text en Copyright © 2023, Tomioka et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Urology
Tomioka, Masayuki
Uno, Hiromi
Seike, Kensaku
Iinuma, Koji
Tatsuhiko, Miyazaki
A Case Report of Syphilis That Was Difficult to Distinguish From Penile Carcinoma
title A Case Report of Syphilis That Was Difficult to Distinguish From Penile Carcinoma
title_full A Case Report of Syphilis That Was Difficult to Distinguish From Penile Carcinoma
title_fullStr A Case Report of Syphilis That Was Difficult to Distinguish From Penile Carcinoma
title_full_unstemmed A Case Report of Syphilis That Was Difficult to Distinguish From Penile Carcinoma
title_short A Case Report of Syphilis That Was Difficult to Distinguish From Penile Carcinoma
title_sort case report of syphilis that was difficult to distinguish from penile carcinoma
topic Urology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566309/
https://www.ncbi.nlm.nih.gov/pubmed/37829948
http://dx.doi.org/10.7759/cureus.45029
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