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Emerging roles of the CIP2A–TopBP1 complex in genome integrity

CIP2A is an inhibitor of the tumour suppressor protein phosphatase 2A. Recently, CIP2A was identified as a synthetic lethal interactor of BRCA1 and BRCA2 and a driver of basal-like breast cancers. In addition, a joint role of TopBP1 (topoisomerase IIβ-binding protein 1) and CIP2A for maintaining gen...

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Detalles Bibliográficos
Autores principales:	Ummethum, Henning, Li, Jiayi, Lisby, Michael, Oestergaard, Vibe H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Short Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566317/ https://www.ncbi.nlm.nih.gov/pubmed/37829116 http://dx.doi.org/10.1093/narcan/zcad052

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