Cargando…
The Inherited KRAS-variant as a Biomarker of Cetuximab Response in NSCLC
PURPOSE: RTOG 0617 was a phase III randomized trial for patients with unresectable stage IIIA/IIIB non–small cell lung cancer comparing standard-dose (60 Gy) versus high-dose (74 Gy) radiotherapy and chemotherapy, plus or minus cetuximab. Although the study was negative, based on prior evidence that...
Autores principales: | Weidhaas, Joanne B., Hu, Chen, Komaki, Ritsuko, Masters, Gregory A., Blumenschein, George R., Chang, Joe Y., Lu, Bo, Dicker, Adam P., Bogart, Jeffrey A., Garces, Yolanda I., Narayan, Samir, Robinson, Clifford G., Kavadi, Vivek S., Greenberger, Joel S., Koprowski, Christopher D., Welsh, James, Gore, Elizabeth M., MacRae, Robert M., Paulus, Rebecca, Bradley, Jeffrey D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566451/ https://www.ncbi.nlm.nih.gov/pubmed/37728512 http://dx.doi.org/10.1158/2767-9764.CRC-23-0084 |
Ejemplares similares
-
Higher Radiation Dose to the Immune Cells Correlates with Worse Tumor Control and Overall Survival in Patients with Stage III NSCLC: A Secondary Analysis of RTOG0617
por: Jin, Jian-Yue, et al.
Publicado: (2021) -
Dasatinib sensitizes KRAS mutant colorectal tumors to cetuximab
por: Dunn, Emily F., et al.
Publicado: (2010) -
Cetuximab–siRNA Conjugate Linked Through Cationized Gelatin Knocks Down KRAS G12C Mutation in NSCLC Sensitizing the Cells Toward Gefitinib
por: Sreedurgalakshmi, K., et al.
Publicado: (2021) -
KRAS in NSCLC: State of the Art and Future Perspectives
por: Cascetta, Priscilla, et al.
Publicado: (2022) -
Osteopontin Mediates Cetuximab Resistance via the MAPK Pathway in NSCLC Cells
por: Cui, Jian, et al.
Publicado: (2019)