A cell-active cyclic peptide targeting the Nrf2/Keap1 protein–protein interaction

The disruption of the protein–protein interaction (PPI) between Nrf2 and Keap1 is an attractive strategy to counteract the oxidative stress that characterises a variety of severe diseases. Peptides represent a complementary approach to small molecules for the inhibition of this therapeutically impor...

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Detalles Bibliográficos
Autores principales: Iegre, Jessica, Krajcovicova, Sona, Gunnarsson, Anders, Wissler, Lisa, Käck, Helena, Luchniak, Anna, Tångefjord, Stefan, Narjes, Frank, Spring, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566475/
https://www.ncbi.nlm.nih.gov/pubmed/37829032
http://dx.doi.org/10.1039/d3sc04083f

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