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An unusual presentation of ossified spinal meningioma: case report and literature review

BACKGROUND: Spinal meningioma is a common intraspinal tumor, which mainly occurs in the thoracic spine. Ossified meningioma (OSM) is an extremely rare histological variant. Our article reports a rare patient with dorsal complete OSM and reviews this subject. CASE PRESENTATION: A 68-year-old woman pr...

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Autores principales: Xu, Wen-Bin, Sun, Nai-Kun, Cai, Di-Xin, Chen, Ding-Qiang, Niu, Yuan, Jia, Fang, Lin, Guang-Xun, Rui, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566645/
https://www.ncbi.nlm.nih.gov/pubmed/37829332
http://dx.doi.org/10.3389/fonc.2023.1259508
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author Xu, Wen-Bin
Sun, Nai-Kun
Cai, Di-Xin
Chen, Ding-Qiang
Niu, Yuan
Jia, Fang
Lin, Guang-Xun
Rui, Gang
author_facet Xu, Wen-Bin
Sun, Nai-Kun
Cai, Di-Xin
Chen, Ding-Qiang
Niu, Yuan
Jia, Fang
Lin, Guang-Xun
Rui, Gang
author_sort Xu, Wen-Bin
collection PubMed
description BACKGROUND: Spinal meningioma is a common intraspinal tumor, which mainly occurs in the thoracic spine. Ossified meningioma (OSM) is an extremely rare histological variant. Our article reports a rare patient with dorsal complete OSM and reviews this subject. CASE PRESENTATION: A 68-year-old woman presented with a one-year history of progressive weakness in both lower limbs with gait disturbance. Physical examination revealed hypoesthesia with a sensory level below T10. Babinski and pathological signs on both sides were weakly positive. Magnetic resonance imaging (MRI) showed a mass at the T10 to T11 level causing severe compression of the spinal cord. Computed tomography (CT) showed complete ossification of the mass. 18F-Fluoro-deoxy-glucose positron emission tomography CT (18F-FDG PET/CT) scan combined with MRI revealed that the mass was an intradural extramedullary high-density ossified nodule. The patient underwent a gross total resection of the mass and pathologic examination indicated that the mass was a meningioma with diffused psammomatous bodies. CONCLUSION: We identified a rare case of dorsal complete OSM occurring in a 68-year-old woman. After complete surgical resection, although there were complications such as cerebral fluid leakage and fever, the patient finally recovered with a satisfactory result.
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spelling pubmed-105666452023-10-12 An unusual presentation of ossified spinal meningioma: case report and literature review Xu, Wen-Bin Sun, Nai-Kun Cai, Di-Xin Chen, Ding-Qiang Niu, Yuan Jia, Fang Lin, Guang-Xun Rui, Gang Front Oncol Oncology BACKGROUND: Spinal meningioma is a common intraspinal tumor, which mainly occurs in the thoracic spine. Ossified meningioma (OSM) is an extremely rare histological variant. Our article reports a rare patient with dorsal complete OSM and reviews this subject. CASE PRESENTATION: A 68-year-old woman presented with a one-year history of progressive weakness in both lower limbs with gait disturbance. Physical examination revealed hypoesthesia with a sensory level below T10. Babinski and pathological signs on both sides were weakly positive. Magnetic resonance imaging (MRI) showed a mass at the T10 to T11 level causing severe compression of the spinal cord. Computed tomography (CT) showed complete ossification of the mass. 18F-Fluoro-deoxy-glucose positron emission tomography CT (18F-FDG PET/CT) scan combined with MRI revealed that the mass was an intradural extramedullary high-density ossified nodule. The patient underwent a gross total resection of the mass and pathologic examination indicated that the mass was a meningioma with diffused psammomatous bodies. CONCLUSION: We identified a rare case of dorsal complete OSM occurring in a 68-year-old woman. After complete surgical resection, although there were complications such as cerebral fluid leakage and fever, the patient finally recovered with a satisfactory result. Frontiers Media S.A. 2023-09-27 /pmc/articles/PMC10566645/ /pubmed/37829332 http://dx.doi.org/10.3389/fonc.2023.1259508 Text en Copyright © 2023 Xu, Sun, Cai, Chen, Niu, Jia, Lin and Rui https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Xu, Wen-Bin
Sun, Nai-Kun
Cai, Di-Xin
Chen, Ding-Qiang
Niu, Yuan
Jia, Fang
Lin, Guang-Xun
Rui, Gang
An unusual presentation of ossified spinal meningioma: case report and literature review
title An unusual presentation of ossified spinal meningioma: case report and literature review
title_full An unusual presentation of ossified spinal meningioma: case report and literature review
title_fullStr An unusual presentation of ossified spinal meningioma: case report and literature review
title_full_unstemmed An unusual presentation of ossified spinal meningioma: case report and literature review
title_short An unusual presentation of ossified spinal meningioma: case report and literature review
title_sort unusual presentation of ossified spinal meningioma: case report and literature review
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566645/
https://www.ncbi.nlm.nih.gov/pubmed/37829332
http://dx.doi.org/10.3389/fonc.2023.1259508
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