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Noncanonical mechanism of Nrf2 activation by diacylglycerol polyethylene glycol adducts in normal human epidermal keratinocytes

Polyethylene glycol-23 glyceryl distearate (GDS-23), a diacylglycerol polyethylene glycol adduct, forms niosomes with a liposome-like structure and functions as an active ingredient in drug delivery systems. In addition, it upregulates antioxidant proteins such as heme oxygenase 1 and NAD(P)H-quinon...

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Detalles Bibliográficos
Autores principales: Miyoshi, Tatsuro, Keller, Brian C., Ashino, Takashi, Numazawa, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10566712/
https://www.ncbi.nlm.nih.gov/pubmed/37819868
http://dx.doi.org/10.1371/journal.pone.0291905