Fluorescein-based sensors to purify human α-cells for functional and transcriptomic analyses

Pancreatic α-cells secrete glucagon, an insulin counter-regulatory peptide hormone critical for the maintenance of glucose homeostasis. Investigation of the function of human α-cells remains a challenge due to the lack of cost-effective purification methods to isolate high-quality α-cells from islet...

Descripción completa

Detalles Bibliográficos
Autores principales: Kahraman, Sevim, Shibue, Kimitaka, De Jesus, Dario F, Kim, Hyunki, Hu, Jiang, Manna, Debasish, Wagner, Bridget, Choudhary, Amit, Kulkarni, Rohit N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567109/
https://www.ncbi.nlm.nih.gov/pubmed/37732504
http://dx.doi.org/10.7554/eLife.85056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567109/
https://www.ncbi.nlm.nih.gov/pubmed/37732504
http://dx.doi.org/10.7554/eLife.85056

Ejemplares similares