Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization

Despite their promise, circulating tumor DNA (ctDNA)-based assays for multi-cancer early detection face challenges in test performance, due mostly to the limited abundance of ctDNA and its inherent variability. To address these challenges, published assays to date demanded a very high-depth sequenci...

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Detalles Bibliográficos
Autores principales: Nguyen, Van Thien Chi, Nguyen, Trong Hieu, Doan, Nhu Nhat Tan, Pham, Thi Mong Quynh, Nguyen, Giang Thi Huong, Nguyen, Thanh Dat, Tran, Thuy Thi Thu, Vo, Duy Long, Phan, Thanh Hai, Jasmine, Thanh Xuan, Nguyen, Van Chu, Nguyen, Huu Thinh, Nguyen, Trieu Vu, Nguyen, Thi Hue Hanh, Huynh, Le Anh Khoa, Tran, Trung Hieu, Dang, Quang Thong, Doan, Thuy Nguyen, Tran, Anh Minh, Nguyen, Viet Hai, Nguyen, Vu Tuan Anh, Ho, Le Minh Quoc, Tran, Quang Dat, Pham, Thi Thu Thuy, Ho, Tan Dat, Nguyen, Bao Toan, Nguyen, Thanh Nhan Vo, Nguyen, Thanh Dang, Phu, Dung Thai Bieu, Phan, Boi Hoan Huu, Vo, Thi Loan, Nai, Thi Huong Thoang, Tran, Thuy Trang, Truong, My Hoang, Tran, Ngan Chau, Le, Trung Kien, Tran, Thanh Huong Thi, Duong, Minh Long, Bach, Hoai Phuong Thi, Kim, Van Vu, Pham, The Anh, Tran, Duc Huy, Le, Trinh Ngoc An, Pham, Truong Vinh Ngoc, Le, Minh Triet, Vo, Dac Ho, Tran, Thi Minh Thu, Nguyen, Minh Nguyen, Van, Thi Tuong Vi, Nguyen, Anh Nhu, Tran, Thi Trang, Tran, Vu Uyen, Le, Minh Phong, Do, Thi Thanh, Phan, Thi Van, Nguyen, Hong-Dang Luu, Nguyen, Duy Sinh, Cao, Van Thinh, Do, Thanh-Thuy Thi, Truong, Dinh Kiet, Tang, Hung Sang, Giang, Hoa, Nguyen, Hoai-Nghia, Phan, Minh-Duy, Tran, Le Son
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567114/
https://www.ncbi.nlm.nih.gov/pubmed/37819044
http://dx.doi.org/10.7554/eLife.89083

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