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Sugammadex-induced bronchospasm: a case report

Sugammadex has shown faster reversal of steroidal neuromuscular blockade (NMB) than neostigmine, a traditional reversal agent for NMB, even in the intense block phase. This efficiency is possible because of the unique mechanism of action by encapsulating the NMB molecules. Therefore, with the use of...

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Autores principales: Kim, Saeyoung, Choo, Hyojun, Jung, Hoon, Kim, Ji Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Dental Society of Anesthsiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567541/
https://www.ncbi.nlm.nih.gov/pubmed/37841521
http://dx.doi.org/10.17245/jdapm.2023.23.5.287
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author Kim, Saeyoung
Choo, Hyojun
Jung, Hoon
Kim, Ji Hyun
author_facet Kim, Saeyoung
Choo, Hyojun
Jung, Hoon
Kim, Ji Hyun
author_sort Kim, Saeyoung
collection PubMed
description Sugammadex has shown faster reversal of steroidal neuromuscular blockade (NMB) than neostigmine, a traditional reversal agent for NMB, even in the intense block phase. This efficiency is possible because of the unique mechanism of action by encapsulating the NMB molecules. Therefore, with the use of sugammadex, we can also expect to avoid direct interactions with the cholinergic system and its subsequent side effects, which are disadvantages of traditional drugs. However, despite these benefits and US Food and Drug Administration (FDA) approval in 2015, rare adverse events associated with sugammadex have been reported. Herein, we report a case of bronchospasm that developed immediately after sugammadex administration.
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spelling pubmed-105675412023-10-13 Sugammadex-induced bronchospasm: a case report Kim, Saeyoung Choo, Hyojun Jung, Hoon Kim, Ji Hyun J Dent Anesth Pain Med Case Report Sugammadex has shown faster reversal of steroidal neuromuscular blockade (NMB) than neostigmine, a traditional reversal agent for NMB, even in the intense block phase. This efficiency is possible because of the unique mechanism of action by encapsulating the NMB molecules. Therefore, with the use of sugammadex, we can also expect to avoid direct interactions with the cholinergic system and its subsequent side effects, which are disadvantages of traditional drugs. However, despite these benefits and US Food and Drug Administration (FDA) approval in 2015, rare adverse events associated with sugammadex have been reported. Herein, we report a case of bronchospasm that developed immediately after sugammadex administration. The Korean Dental Society of Anesthsiology 2023-10 2023-09-27 /pmc/articles/PMC10567541/ /pubmed/37841521 http://dx.doi.org/10.17245/jdapm.2023.23.5.287 Text en Copyright © 2023 Journal of Dental Anesthesia and Pain Medicine https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kim, Saeyoung
Choo, Hyojun
Jung, Hoon
Kim, Ji Hyun
Sugammadex-induced bronchospasm: a case report
title Sugammadex-induced bronchospasm: a case report
title_full Sugammadex-induced bronchospasm: a case report
title_fullStr Sugammadex-induced bronchospasm: a case report
title_full_unstemmed Sugammadex-induced bronchospasm: a case report
title_short Sugammadex-induced bronchospasm: a case report
title_sort sugammadex-induced bronchospasm: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567541/
https://www.ncbi.nlm.nih.gov/pubmed/37841521
http://dx.doi.org/10.17245/jdapm.2023.23.5.287
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