A maternally programmed intergenerational mechanism enables male offspring to make piRNAs from Y-linked precursor RNAs in Drosophila

In animals, PIWI-interacting RNAs (piRNAs) direct PIWI proteins to silence complementary targets such as transposons. In Drosophila and other species with a maternally specified germline, piRNAs deposited in the egg initiate piRNA biogenesis in the progeny. However, Y chromosome loci cannot particip...

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Detalles Bibliográficos
Autores principales: Venkei, Zsolt G., Gainetdinov, Ildar, Bagci, Ayca, Starostik, Margaret R., Choi, Charlotte P., Fingerhut, Jaclyn M., Chen, Peiwei, Balsara, Chiraag, Whitfield, Troy W., Bell, George W., Feng, Suhua, Jacobsen, Steven E., Aravin, Alexei A., Kim, John K., Zamore, Phillip D., Yamashita, Yukiko M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567549/
https://www.ncbi.nlm.nih.gov/pubmed/37723298
http://dx.doi.org/10.1038/s41556-023-01227-4

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