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Myc-dependent dedifferentiation of Gata6(+) epidermal cells resembles reversal of terminal differentiation

Dedifferentiation is the process by which terminally differentiated cells acquire the properties of stem cells. During mouse skin wound healing, the differentiated Gata6-lineage positive cells of the sebaceous duct are able to dedifferentiate. Here we have integrated lineage tracing and single-cell...

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Detalles Bibliográficos
Autores principales: Bernabé-Rubio, Miguel, Ali, Shahnawaz, Bhosale, Priyanka G., Goss, Georgina, Mobasseri, Seyedeh Atefeh, Tapia-Rojo, Rafael, Zhu, Tong, Hiratsuka, Toru, Battilocchi, Matteo, Tomás, Inês M., Ganier, Clarisse, Garcia-Manyes, Sergi, Watt, Fiona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567550/
https://www.ncbi.nlm.nih.gov/pubmed/37735598
http://dx.doi.org/10.1038/s41556-023-01234-5