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Myc-dependent dedifferentiation of Gata6(+) epidermal cells resembles reversal of terminal differentiation
Dedifferentiation is the process by which terminally differentiated cells acquire the properties of stem cells. During mouse skin wound healing, the differentiated Gata6-lineage positive cells of the sebaceous duct are able to dedifferentiate. Here we have integrated lineage tracing and single-cell...
Autores principales: | Bernabé-Rubio, Miguel, Ali, Shahnawaz, Bhosale, Priyanka G., Goss, Georgina, Mobasseri, Seyedeh Atefeh, Tapia-Rojo, Rafael, Zhu, Tong, Hiratsuka, Toru, Battilocchi, Matteo, Tomás, Inês M., Ganier, Clarisse, Garcia-Manyes, Sergi, Watt, Fiona M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567550/ https://www.ncbi.nlm.nih.gov/pubmed/37735598 http://dx.doi.org/10.1038/s41556-023-01234-5 |
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