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piRNA processing by a trimeric Schlafen-domain nuclease

Transposable elements are genomic parasites that expand within and spread between genomes(1). PIWI proteins control transposon activity, notably in the germline(2,3). These proteins recognize their targets through small RNA co-factors named PIWI-interacting RNAs (piRNAs), making piRNA biogenesis a k...

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Detalles Bibliográficos
Autores principales: Podvalnaya, Nadezda, Bronkhorst, Alfred W., Lichtenberger, Raffael, Hellmann, Svenja, Nischwitz, Emily, Falk, Torben, Karaulanov, Emil, Butter, Falk, Falk, Sebastian, Ketting, René F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567574/
https://www.ncbi.nlm.nih.gov/pubmed/37758951
http://dx.doi.org/10.1038/s41586-023-06588-2

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