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Curved adhesions mediate cell attachment to soft matrix fibres in three dimensions
Integrin-mediated focal adhesions are the primary architectures that transmit forces between the extracellular matrix (ECM) and the actin cytoskeleton. Although focal adhesions are abundant on rigid and flat substrates that support high mechanical tensions, they are sparse in soft three-dimensional...
Autores principales: | Zhang, Wei, Lu, Chih-Hao, Nakamoto, Melissa L., Tsai, Ching-Ting, Roy, Anish R., Lee, Christina E., Yang, Yang, Jahed, Zeinab, Li, Xiao, Cui, Bianxiao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567576/ https://www.ncbi.nlm.nih.gov/pubmed/37770566 http://dx.doi.org/10.1038/s41556-023-01238-1 |
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