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Chemoresistant fibroblasts dictate neoadjuvant chemotherapeutic response of head and neck cancer via TGFα-EGFR paracrine signaling

Conventional chemotherapy targets malignant cells without evaluating counter protection from the tumor microenvironment that often causes treatment failure. Herein, we establish chemoresistant fibroblasts (rCAFs) as regulators of neoadjuvant chemotherapeutic (NACT) response in head and neck squamous...

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Detalles Bibliográficos
Autores principales:	Su, Liangping, Wu, Sangqing, Huang, Cheng, Zhuo, Xianhua, Chen, Jiali, Jiang, Xue, Kong, Xiangzhan, Lv, Cui, Xu, Qiuping, Han, Ping, Huang, Xiaoming, Wong, Ping-Pui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567732/ https://www.ncbi.nlm.nih.gov/pubmed/37821657 http://dx.doi.org/10.1038/s41698-023-00460-2

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