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Depressive states in healthy subjects lead to biased processing in frontal-parietal ERPs during emotional stimuli
Subthreshold depressive (sD) states and major depression are considered to occur on a continuum, and there are only quantitative and not qualitative differences between depressive states in healthy individuals and patients with depression. sD is showing a progressively increasing prevalence and has...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567753/ https://www.ncbi.nlm.nih.gov/pubmed/37821575 http://dx.doi.org/10.1038/s41598-023-44368-0 |
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author | Li, Pengcheng Yokoyama, Mio Okamoto, Daiki Nakatani, Hironori Yagi, Tohru |
author_facet | Li, Pengcheng Yokoyama, Mio Okamoto, Daiki Nakatani, Hironori Yagi, Tohru |
author_sort | Li, Pengcheng |
collection | PubMed |
description | Subthreshold depressive (sD) states and major depression are considered to occur on a continuum, and there are only quantitative and not qualitative differences between depressive states in healthy individuals and patients with depression. sD is showing a progressively increasing prevalence and has a lifelong impact, and the social and clinical impacts of sD are no less than those of major depressive disorder (MDD). Because depression leads to biased cognition, patients with depression and healthy individuals show different visual processing properties. However, it remains unclear whether there are significant differences in visual information recognition among healthy individuals with various depressive states. In this study, we investigated the event-related potentials (ERPs) and event-related spectrum perturbation (ERSP) of healthy individuals with various depressive states during the perception of emotional visual stimulation. We show that different neural activities can be detected even among healthy individuals. We divided healthy participants into high, middle, and low depressive state groups and found that participants in a high depressive state had a lower P300 amplitude and significant differences in fast and slow neural responses in the frontal and parietal lobes. We anticipate our study to provide useful parameters for assessing the evaluation of depressive states in healthy individuals. |
format | Online Article Text |
id | pubmed-10567753 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-105677532023-10-13 Depressive states in healthy subjects lead to biased processing in frontal-parietal ERPs during emotional stimuli Li, Pengcheng Yokoyama, Mio Okamoto, Daiki Nakatani, Hironori Yagi, Tohru Sci Rep Article Subthreshold depressive (sD) states and major depression are considered to occur on a continuum, and there are only quantitative and not qualitative differences between depressive states in healthy individuals and patients with depression. sD is showing a progressively increasing prevalence and has a lifelong impact, and the social and clinical impacts of sD are no less than those of major depressive disorder (MDD). Because depression leads to biased cognition, patients with depression and healthy individuals show different visual processing properties. However, it remains unclear whether there are significant differences in visual information recognition among healthy individuals with various depressive states. In this study, we investigated the event-related potentials (ERPs) and event-related spectrum perturbation (ERSP) of healthy individuals with various depressive states during the perception of emotional visual stimulation. We show that different neural activities can be detected even among healthy individuals. We divided healthy participants into high, middle, and low depressive state groups and found that participants in a high depressive state had a lower P300 amplitude and significant differences in fast and slow neural responses in the frontal and parietal lobes. We anticipate our study to provide useful parameters for assessing the evaluation of depressive states in healthy individuals. Nature Publishing Group UK 2023-10-11 /pmc/articles/PMC10567753/ /pubmed/37821575 http://dx.doi.org/10.1038/s41598-023-44368-0 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Li, Pengcheng Yokoyama, Mio Okamoto, Daiki Nakatani, Hironori Yagi, Tohru Depressive states in healthy subjects lead to biased processing in frontal-parietal ERPs during emotional stimuli |
title | Depressive states in healthy subjects lead to biased processing in frontal-parietal ERPs during emotional stimuli |
title_full | Depressive states in healthy subjects lead to biased processing in frontal-parietal ERPs during emotional stimuli |
title_fullStr | Depressive states in healthy subjects lead to biased processing in frontal-parietal ERPs during emotional stimuli |
title_full_unstemmed | Depressive states in healthy subjects lead to biased processing in frontal-parietal ERPs during emotional stimuli |
title_short | Depressive states in healthy subjects lead to biased processing in frontal-parietal ERPs during emotional stimuli |
title_sort | depressive states in healthy subjects lead to biased processing in frontal-parietal erps during emotional stimuli |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567753/ https://www.ncbi.nlm.nih.gov/pubmed/37821575 http://dx.doi.org/10.1038/s41598-023-44368-0 |
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