Human equivalent doses of l-DOPA rescues retinal morphology and visual function in a murine model of albinism

l-DOPA is deficient in the developing albino eye, resulting in abnormalities of retinal development and visual impairment. Ongoing retinal development after birth has also been demonstrated in the developing albino eye offering a potential therapeutic window in humans. To study whether human equival...

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Detalles Bibliográficos
Autores principales: Sanchez-Bretano, Aida, Keeling, Eloise, Scott, Jennifer A., Lynn, Savannah A., Soundara-Pandi, Sudha Priya, Macdonald, Sarah L., Newall, Tutte, Griffiths, Helen, Lotery, Andrew J., Ratnayaka, J. Arjuna, Self, Jay E., Lee, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567794/
https://www.ncbi.nlm.nih.gov/pubmed/37821525
http://dx.doi.org/10.1038/s41598-023-44373-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567794/
https://www.ncbi.nlm.nih.gov/pubmed/37821525
http://dx.doi.org/10.1038/s41598-023-44373-3

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