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Human equivalent doses of l-DOPA rescues retinal morphology and visual function in a murine model of albinism
l-DOPA is deficient in the developing albino eye, resulting in abnormalities of retinal development and visual impairment. Ongoing retinal development after birth has also been demonstrated in the developing albino eye offering a potential therapeutic window in humans. To study whether human equival...
Autores principales: | Sanchez-Bretano, Aida, Keeling, Eloise, Scott, Jennifer A., Lynn, Savannah A., Soundara-Pandi, Sudha Priya, Macdonald, Sarah L., Newall, Tutte, Griffiths, Helen, Lotery, Andrew J., Ratnayaka, J. Arjuna, Self, Jay E., Lee, Helena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567794/ https://www.ncbi.nlm.nih.gov/pubmed/37821525 http://dx.doi.org/10.1038/s41598-023-44373-3 |
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