Cargando…
Expression of viral CD45 ligand E3/49K on porcine cells reduces human anti-pig immune responses
Transgenic expression of protective molecules in porcine cells and tissues is a promising approach to prevent xenograft rejection. Viruses have developed various strategies to escape the host’s immune system. We generated porcine B cells (B cell line L23) expressing the human adenovirus protein E3/4...
Autores principales: | Pokoyski, Claudia, Baars, Wiebke, Windheim, Mark, Reubold, Thomas F., Zischke, Jasmin, Brinkmann, Antje, Kay-Fedorov, Penelope C., Schwinzer, Reinhard |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567836/ https://www.ncbi.nlm.nih.gov/pubmed/37821577 http://dx.doi.org/10.1038/s41598-023-44316-y |
Ejemplares similares
-
Viral Interference with Functions of the Cellular Receptor Tyrosine Phosphatase CD45
por: Thiel, Nadine, et al.
Publicado: (2015) -
Human Cytomegalovirus pUL11, a CD45 Ligand, Disrupts CD4 T Cell Control of Viral Spread in Epithelial Cells
por: Osanyinlusi, Samuel A., et al.
Publicado: (2022) -
The human cytomegalovirus glycoprotein pUL11 acts via CD45 to induce T cell IL-10 secretion
por: Zischke, Jasmin, et al.
Publicado: (2017) -
The Human Cytomegalovirus UL11 Protein Interacts with the Receptor Tyrosine Phosphatase CD45, Resulting in Functional Paralysis of T Cells
por: Gabaev, Ildar, et al.
Publicado: (2011) -
The c.503T>C Polymorphism in the Human KLRB1 Gene Alters Ligand Binding and Inhibitory Potential of CD161 Molecules
por: Rother, Sascha, et al.
Publicado: (2015)