Species-differences in the in vitro biotransformation of trifluoroethene (HFO-1123)

1,1,2-Trifluoroethene (HFO-1123) is anticipated for use as a refrigerant with low global warming potential. Inhalation studies on HFO-1123 in rats indicated a low potential for toxicity (NOAELs ≥ 20,000 ppm). In contrast, single inhalation exposure of Goettingen(®) minipigs (≥ 500 ppm) and New Zeala...

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Detalles Bibliográficos
Autores principales: Dekant, R., Bertermann, R., Serban, J., Sharma, S., Shinohara, M., Morizawa, Y., Okamoto, H., Brock, W., Dekant, W., Mally, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Toxicokinetics and Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567879/
https://www.ncbi.nlm.nih.gov/pubmed/37792044
http://dx.doi.org/10.1007/s00204-023-03603-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567879/
https://www.ncbi.nlm.nih.gov/pubmed/37792044
http://dx.doi.org/10.1007/s00204-023-03603-3

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