A clock-dependent brake for rhythmic arousal in the dorsomedial hypothalamus

Circadian clocks generate rhythms of arousal, but the underlying molecular and cellular mechanisms remain unclear. In Drosophila, the clock output molecule WIDE AWAKE (WAKE) labels rhythmic neural networks and cyclically regulates sleep and arousal. Here, we show, in a male mouse model, that mWAKE/A...

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Detalles Bibliográficos
Autores principales: Liu, Qiang, Bell, Benjamin J., Kim, Dong Won, Lee, Sang Soo, Keles, Mehmet F., Liu, Qili, Blum, Ian D., Wang, Annette A., Blank, Elijah J., Xiong, Jiali, Bedont, Joseph L., Chang, Anna J., Issa, Habon, Cohen, Jeremiah Y., Blackshaw, Seth, Wu, Mark N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567910/
https://www.ncbi.nlm.nih.gov/pubmed/37821426
http://dx.doi.org/10.1038/s41467-023-41877-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567910/
https://www.ncbi.nlm.nih.gov/pubmed/37821426
http://dx.doi.org/10.1038/s41467-023-41877-4

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