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Peripheral temperature dysregulation associated with functionally altered Na(V)1.8 channels
The voltage-gated sodium channel Na(V)1.8 is prominently expressed in the soma and axons of small-caliber sensory neurons, and pathogenic variants of the corresponding gene SCN10A are associated with peripheral pain and autonomic dysfunction. While most disease-associated SCN10A variants confer gain...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10567936/ https://www.ncbi.nlm.nih.gov/pubmed/37695396 http://dx.doi.org/10.1007/s00424-023-02856-2 |