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Photodynamic therapy and associated targeting methods for treatment of brain cancer

Brain tumors, including glioblastoma multiforme, are currently a cause of suffering and death of tens of thousands of people worldwide. Despite advances in clinical treatment, the average patient survival time from the moment of diagnosis of glioblastoma multiforme and application of standard treatm...

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Autores principales: Bartusik-Aebisher, Dorota, Serafin, Iga, Dynarowicz, Klaudia, Aebisher, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568033/
https://www.ncbi.nlm.nih.gov/pubmed/37841921
http://dx.doi.org/10.3389/fphar.2023.1250699
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author Bartusik-Aebisher, Dorota
Serafin, Iga
Dynarowicz, Klaudia
Aebisher, David
author_facet Bartusik-Aebisher, Dorota
Serafin, Iga
Dynarowicz, Klaudia
Aebisher, David
author_sort Bartusik-Aebisher, Dorota
collection PubMed
description Brain tumors, including glioblastoma multiforme, are currently a cause of suffering and death of tens of thousands of people worldwide. Despite advances in clinical treatment, the average patient survival time from the moment of diagnosis of glioblastoma multiforme and application of standard treatment methods such as surgical resection, radio- and chemotherapy, is less than 4 years. The continuing development of new therapeutic methods for targeting and treating brain tumors may extend life and provide greater comfort to patients. One such developing therapeutic method is photodynamic therapy. Photodynamic therapy is a progressive method of therapy used in dermatology, dentistry, ophthalmology, and has found use as an antimicrobial agent. It has also found wide application in photodiagnosis. Photodynamic therapy requires the presence of three necessary components: a clinically approved photosensitizer, oxygen and light. This paper is a review of selected literature from Pubmed and Scopus scientific databases in the field of photodynamic therapy in brain tumors with an emphasis on glioblastoma treatment.
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spelling pubmed-105680332023-10-13 Photodynamic therapy and associated targeting methods for treatment of brain cancer Bartusik-Aebisher, Dorota Serafin, Iga Dynarowicz, Klaudia Aebisher, David Front Pharmacol Pharmacology Brain tumors, including glioblastoma multiforme, are currently a cause of suffering and death of tens of thousands of people worldwide. Despite advances in clinical treatment, the average patient survival time from the moment of diagnosis of glioblastoma multiforme and application of standard treatment methods such as surgical resection, radio- and chemotherapy, is less than 4 years. The continuing development of new therapeutic methods for targeting and treating brain tumors may extend life and provide greater comfort to patients. One such developing therapeutic method is photodynamic therapy. Photodynamic therapy is a progressive method of therapy used in dermatology, dentistry, ophthalmology, and has found use as an antimicrobial agent. It has also found wide application in photodiagnosis. Photodynamic therapy requires the presence of three necessary components: a clinically approved photosensitizer, oxygen and light. This paper is a review of selected literature from Pubmed and Scopus scientific databases in the field of photodynamic therapy in brain tumors with an emphasis on glioblastoma treatment. Frontiers Media S.A. 2023-09-28 /pmc/articles/PMC10568033/ /pubmed/37841921 http://dx.doi.org/10.3389/fphar.2023.1250699 Text en Copyright © 2023 Bartusik-Aebisher, Serafin, Dynarowicz and Aebisher. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Bartusik-Aebisher, Dorota
Serafin, Iga
Dynarowicz, Klaudia
Aebisher, David
Photodynamic therapy and associated targeting methods for treatment of brain cancer
title Photodynamic therapy and associated targeting methods for treatment of brain cancer
title_full Photodynamic therapy and associated targeting methods for treatment of brain cancer
title_fullStr Photodynamic therapy and associated targeting methods for treatment of brain cancer
title_full_unstemmed Photodynamic therapy and associated targeting methods for treatment of brain cancer
title_short Photodynamic therapy and associated targeting methods for treatment of brain cancer
title_sort photodynamic therapy and associated targeting methods for treatment of brain cancer
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568033/
https://www.ncbi.nlm.nih.gov/pubmed/37841921
http://dx.doi.org/10.3389/fphar.2023.1250699
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