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Substantiation of a clopidogrel metabolism-associated gene (CYP2C19) variation among healthy individuals

BACKGROUND: It is essential to investigate the prevalence of CYP2C19 alleles that affect drug metabolism. This study measures the allelic and genotypic frequencies of CYP2C19 loss-of-function (LoF) alleles CYP2C19∗2, CYP2C19∗3, and gain-of-function (GoF) alleles CYP2C19∗17 in the general population....

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Detalles Bibliográficos
Autores principales:	Yadav, Anshu Kumar, Chakkumkollath, Aparna Kodakkat, Helna, Aysha, Birla, Siddharth, Thimmulappa, Rajesh Kumar, Shambu, Sunil Kumar, Vishwanath, Prashant, Prashant, Akila
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568051/ https://www.ncbi.nlm.nih.gov/pubmed/37217095 http://dx.doi.org/10.1016/j.ihj.2023.05.005

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