Gut microbiota-based pharmacokinetic-pharmacodynamic study and molecular mechanism of specnuezhenide in the treatment of colorectal cancer targeting carboxylesterase

Specnuezhenide (SNZ) is among the main components of Fructus Ligustri Lucidi, which has anti-inflammation, anti-oxidation, and anti-tumor effect. The low bioavailability makes it difficult to explain the mechanism of pharmacological effect of SNZ. In this study, the role of the gut microbiota in the...

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Detalles Bibliográficos
Autores principales: Yu, Hang, Xu, Hui, Yang, Xinyu, Zhang, Zhengwei, Hu, Jiachun, Lu, Jinyue, Fu, Jie, Bu, Mengmeng, Zhang, Haojian, Zhai, Zhao, Wang, Jingyue, Jiang, Jiandong, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568112/
https://www.ncbi.nlm.nih.gov/pubmed/37842660
http://dx.doi.org/10.1016/j.jpha.2023.06.012

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