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Blockade of PD-1 and LAG-3 expression on CD8+ T cells promotes the tumoricidal effects of CD8+ T cells

BACKGROUND: The diffuse large B-cell lymphoma (DLBCL) has the highest incidence of all lymphomas worldwide. To investigate the functions of lymphocyte activation gene 3 (LAG-3) and programmed cell death 1 (PD-1) in tissues and peripheral blood of patients with DLBCL, the expression of LAG-3 and PD-1...

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Detalles Bibliográficos
Autores principales: Ma, Jiajia, Yan, Shufang, Zhao, Ying, Yan, Huifang, Zhang, Qian, Li, Xinxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568325/
https://www.ncbi.nlm.nih.gov/pubmed/37841254
http://dx.doi.org/10.3389/fimmu.2023.1265255