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TWN-FS method: A novel fragment screening method for drug discovery
Fragment-based drug discovery (FBDD) is a well-established and effective method for generating diverse and novel hits in drug design. Kinases are suitable targets for FBDD due to their well-defined structure. Water molecules contribute to structure and function of proteins and also influence the env...
Autores principales: | Yoon, Hye Ree, Park, Gyoung Jin, Balupuri, Anand, Kang, Nam Sook |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568351/ https://www.ncbi.nlm.nih.gov/pubmed/37841326 http://dx.doi.org/10.1016/j.csbj.2023.09.037 |
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