Targeting adrenergic receptors to mitigate invariant natural killer T cells-induced acute liver injury

Invariant Natural Killer T (iNKT) cell activation by α-galactosylceramide (αGC) potentiates cytotoxic immune responses against tumors. However, αGC-induced liver injury is a limiting factor for iNKT-based immunotherapy. Although adrenergic receptor stimulation is an important immunosuppressive signa...

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Detalles Bibliográficos
Autores principales: Gonzatti, Michelangelo Bauwelz, Freire, Beatriz Marton, Antunes, Maísa Mota, de Menezes, Gustavo Batista, Talbot, Jhimmy, Peron, Jean Pierre Schatzmann, Basso, Alexandre Salgado, Keller, Alexandre Castro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568435/
https://www.ncbi.nlm.nih.gov/pubmed/37841583
http://dx.doi.org/10.1016/j.isci.2023.107947

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