Cargando…
Prevalence of cerebral palsy comorbidities in China: a systematic review and meta-analysis
OBJECTIVES: This systematic review aimed to comprehensively understand the comorbidity of cerebral palsy (CP) in China. METHODS: We searched through databases in both Chinese and English until December 2022 to gather cross-sectional studies on the comorbidity of CP in China. After two reviewers inde...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568468/ https://www.ncbi.nlm.nih.gov/pubmed/37840931 http://dx.doi.org/10.3389/fneur.2023.1233700 |
_version_ | 1785119367042695168 |
---|---|
author | Gong, Chao Liu, Xiaopei Fang, Liya Liu, Annan Lian, Beibei Qi, Xunzhong Chen, Shuyue Li, Huiqing Zhao, Ming Guo, Jin Zhou, Shaobo |
author_facet | Gong, Chao Liu, Xiaopei Fang, Liya Liu, Annan Lian, Beibei Qi, Xunzhong Chen, Shuyue Li, Huiqing Zhao, Ming Guo, Jin Zhou, Shaobo |
author_sort | Gong, Chao |
collection | PubMed |
description | OBJECTIVES: This systematic review aimed to comprehensively understand the comorbidity of cerebral palsy (CP) in China. METHODS: We searched through databases in both Chinese and English until December 2022 to gather cross-sectional studies on the comorbidity of CP in China. After two reviewers independently screened the articles, collected the data, and assessed the bias risk, a meta-analysis was conducted using the Stata 17.0 software. RESULTS: A total of 73 articles were included. Of these, 16 articles reported total comorbidity, with a prevalence of 79.7% (95% CI: 73.8–85.7%); 56 articles reported epilepsy, with a prevalence of 17.9% (95% CI: 15.4–20.4%); 48 articles reported intellectual disability, with a prevalence of 58.0% (95% CI: 51.8–64.3%); 32 articles reported speech disorders, with a prevalence of 48.0% (95% CI: 41.6–54.4%); 41 articles reported hearing disorders, with a prevalence of 17.2% (95% CI: 13.0–21.4%); and 35 articles reported vision disorders, with a prevalence of 23.1% (95% CI: 16.3–29.8%). The topographical type of CP was the primary source of heterogeneity in the prevalence of epilepsy. Diagnostic criteria for CP, clinical type of CP, GMFCS, publishing time, and topographical type of CP were the primary sources of heterogeneity in the prevalence of intellectual disability. Clinical type of CP and topographical type were the primary sources of heterogeneity in the prevalence of speech disorders. Finally, the region was the primary source of heterogeneity in the prevalence of hearing disorders. CONCLUSION: The prevalence of comorbidities in CP is high in China. Comorbidities are related to the characteristics, severity, and risk factors of brain insult and have a particular relationship with regional economic development and medical and health levels. |
format | Online Article Text |
id | pubmed-10568468 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-105684682023-10-13 Prevalence of cerebral palsy comorbidities in China: a systematic review and meta-analysis Gong, Chao Liu, Xiaopei Fang, Liya Liu, Annan Lian, Beibei Qi, Xunzhong Chen, Shuyue Li, Huiqing Zhao, Ming Guo, Jin Zhou, Shaobo Front Neurol Neurology OBJECTIVES: This systematic review aimed to comprehensively understand the comorbidity of cerebral palsy (CP) in China. METHODS: We searched through databases in both Chinese and English until December 2022 to gather cross-sectional studies on the comorbidity of CP in China. After two reviewers independently screened the articles, collected the data, and assessed the bias risk, a meta-analysis was conducted using the Stata 17.0 software. RESULTS: A total of 73 articles were included. Of these, 16 articles reported total comorbidity, with a prevalence of 79.7% (95% CI: 73.8–85.7%); 56 articles reported epilepsy, with a prevalence of 17.9% (95% CI: 15.4–20.4%); 48 articles reported intellectual disability, with a prevalence of 58.0% (95% CI: 51.8–64.3%); 32 articles reported speech disorders, with a prevalence of 48.0% (95% CI: 41.6–54.4%); 41 articles reported hearing disorders, with a prevalence of 17.2% (95% CI: 13.0–21.4%); and 35 articles reported vision disorders, with a prevalence of 23.1% (95% CI: 16.3–29.8%). The topographical type of CP was the primary source of heterogeneity in the prevalence of epilepsy. Diagnostic criteria for CP, clinical type of CP, GMFCS, publishing time, and topographical type of CP were the primary sources of heterogeneity in the prevalence of intellectual disability. Clinical type of CP and topographical type were the primary sources of heterogeneity in the prevalence of speech disorders. Finally, the region was the primary source of heterogeneity in the prevalence of hearing disorders. CONCLUSION: The prevalence of comorbidities in CP is high in China. Comorbidities are related to the characteristics, severity, and risk factors of brain insult and have a particular relationship with regional economic development and medical and health levels. Frontiers Media S.A. 2023-09-28 /pmc/articles/PMC10568468/ /pubmed/37840931 http://dx.doi.org/10.3389/fneur.2023.1233700 Text en Copyright © 2023 Gong, Liu, Fang, Liu, Lian, Qi, Chen, Li, Zhao, Guo and Zhou. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neurology Gong, Chao Liu, Xiaopei Fang, Liya Liu, Annan Lian, Beibei Qi, Xunzhong Chen, Shuyue Li, Huiqing Zhao, Ming Guo, Jin Zhou, Shaobo Prevalence of cerebral palsy comorbidities in China: a systematic review and meta-analysis |
title | Prevalence of cerebral palsy comorbidities in China: a systematic review and meta-analysis |
title_full | Prevalence of cerebral palsy comorbidities in China: a systematic review and meta-analysis |
title_fullStr | Prevalence of cerebral palsy comorbidities in China: a systematic review and meta-analysis |
title_full_unstemmed | Prevalence of cerebral palsy comorbidities in China: a systematic review and meta-analysis |
title_short | Prevalence of cerebral palsy comorbidities in China: a systematic review and meta-analysis |
title_sort | prevalence of cerebral palsy comorbidities in china: a systematic review and meta-analysis |
topic | Neurology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568468/ https://www.ncbi.nlm.nih.gov/pubmed/37840931 http://dx.doi.org/10.3389/fneur.2023.1233700 |
work_keys_str_mv | AT gongchao prevalenceofcerebralpalsycomorbiditiesinchinaasystematicreviewandmetaanalysis AT liuxiaopei prevalenceofcerebralpalsycomorbiditiesinchinaasystematicreviewandmetaanalysis AT fangliya prevalenceofcerebralpalsycomorbiditiesinchinaasystematicreviewandmetaanalysis AT liuannan prevalenceofcerebralpalsycomorbiditiesinchinaasystematicreviewandmetaanalysis AT lianbeibei prevalenceofcerebralpalsycomorbiditiesinchinaasystematicreviewandmetaanalysis AT qixunzhong prevalenceofcerebralpalsycomorbiditiesinchinaasystematicreviewandmetaanalysis AT chenshuyue prevalenceofcerebralpalsycomorbiditiesinchinaasystematicreviewandmetaanalysis AT lihuiqing prevalenceofcerebralpalsycomorbiditiesinchinaasystematicreviewandmetaanalysis AT zhaoming prevalenceofcerebralpalsycomorbiditiesinchinaasystematicreviewandmetaanalysis AT guojin prevalenceofcerebralpalsycomorbiditiesinchinaasystematicreviewandmetaanalysis AT zhoushaobo prevalenceofcerebralpalsycomorbiditiesinchinaasystematicreviewandmetaanalysis |