Evaluation of zero counts to better understand the discrepancies between bulk and single-cell RNA-Seq platforms

Recent advances in sample preparation and sequencing technology have made it possible to profile the transcriptomes of individual cells using single-cell RNA sequencing (scRNA-Seq). Compared to bulk RNA-Seq data, single-cell data often contain a higher percentage of zero reads, mainly due to lower s...

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Detalles Bibliográficos
Autores principales: Zyla, Joanna, Papiez, Anna, Zhao, Jun, Qu, Rihao, Li, Xiaotong, Kluger, Yuval, Polanska, Joanna, Hatzis, Christos, Pusztai, Lajos, Marczyk, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568495/
https://www.ncbi.nlm.nih.gov/pubmed/37841335
http://dx.doi.org/10.1016/j.csbj.2023.09.035

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