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Results from three phase 1 trials of NNC9204-1177, a glucagon/GLP-1 receptor co-agonist: Effects on weight loss and safety in adults with overweight or obesity
OBJECTIVE: Glucagon/glucagon-like peptide-1 (GLP-1) receptor co-agonists may provide greater weight loss than agonists targeting the GLP-1 receptor alone. We report results from three phase 1 trials investigating the safety, tolerability, pharmacokinetics and pharmacodynamics of the glucagon/GLP-1 r...
Autores principales: | Friedrichsen, Martin Haljeta, Endahl, Lars, Kreiner, Frederik Flindt, Goldwater, Ronald, Kankam, Martin, Toubro, Søren, Nygård, Sune Boris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568562/ https://www.ncbi.nlm.nih.gov/pubmed/37690519 http://dx.doi.org/10.1016/j.molmet.2023.101801 |
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