Whole exome sequencing identifies novel variants of PIK3CA and validation of hotspot mutation by droplet digital PCR in breast cancer among Indian population

BACKGROUND: Breast cancer (BC) is the most common malignancy with very high incidence and relatively high mortality in women. The PIK3CA gene plays a pivotal role in the pathogenicity of breast cancer. Despite this, the mutational status of all exons except exons 9 and 20 still remains unknown. METH...

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Detalles Bibliográficos
Autores principales: Kumar, Rahul, Kumar, Rakesh, Goel, Harsh, Kumar, Sonu, Ningombam, Somorjit Singh, Haider, Imran, Agrawal, Usha, Deo, Svs, Gogia, Ajay, Batra, Atul, Sharma, Ashok, Mathur, Sandeep, Ranjan, Amar, Chopra, Anita, Hussain, Showket, Tanwar, Pranay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568783/
https://www.ncbi.nlm.nih.gov/pubmed/37821962
http://dx.doi.org/10.1186/s12935-023-03075-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568783/
https://www.ncbi.nlm.nih.gov/pubmed/37821962
http://dx.doi.org/10.1186/s12935-023-03075-6

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