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DENV-2 NS1 promotes AMPK-LKB1 interaction to activate AMPK/ERK/mTOR signaling pathway to induce autophagy

The global incidence of dengue fever has gradually increased in recent years, posing a serious threat to human health. In the absence of specific anti-dengue drugs, understanding the interaction of Dengue virus (DENV) with the host is essential for the development of effective therapeutic measures....

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Detalles Bibliográficos
Autores principales: Wu, Ning, Ji, Jinzhong, Gou, Xiaoqin, Hu, Pan, Cheng, Yao, Liu, Yuhang, Wang, Yuanying, Zhang, Qilong, Zuo, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568820/
https://www.ncbi.nlm.nih.gov/pubmed/37821951
http://dx.doi.org/10.1186/s12985-023-02166-0