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Bioinformatic analysis of highly consumed phytochemicals as P-gp binders to overcome drug-resistance

BACKGROUND AND PURPOSE: P-glycoprotein (P-gp) is an adenosine triphosphate (ATP)-dependent membrane efflux pump for protecting cells against xenobiotic compounds. Unfortunately, overexpressed P-gp in neoplastic cells prevents cell entry of numerous chemotherapeutic agents leading to multidrug resist...

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Detalles Bibliográficos
Autores principales:	Rajaei, Narges, Rahgouy, Ghazaleh, Panahi, Nasrin, Razzaghi-Asl, Nima
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10568960/ https://www.ncbi.nlm.nih.gov/pubmed/37842517 http://dx.doi.org/10.4103/1735-5362.383706

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