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An Ionizable Lipid Material with a Vitamin E Scaffold as an mRNA Vaccine Platform for Efficient Cytotoxic T Cell Responses

[Image: see text] RNA vaccines based on lipid nanoparticles (LNPs) with in vitro transcribed mRNA (IVT-mRNA) encapsulated are now a currently successful but still evolving modality of vaccines. One of the advantages of RNA vaccines is their ability to induce CD8(+) T-cell-mediated cellular immunity...

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Detalles Bibliográficos
Autores principales:	Oyama, Ryotaro, Ishigame, Harumichi, Tanaka, Hiroki, Tateshita, Naho, Itazawa, Moeko, Imai, Ryosuke, Nishiumi, Naomasa, Kishikawa, Jun-ichi, Kato, Takayuki, Anindita, Jessica, Nishikawa, Yoshifumi, Maeki, Masatoshi, Tokeshi, Manabu, Tange, Kota, Nakai, Yuta, Sakurai, Yu, Okada, Takaharu, Akita, Hidetaka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569098/ https://www.ncbi.nlm.nih.gov/pubmed/37814788 http://dx.doi.org/10.1021/acsnano.3c02251

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