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Olfactory neurogenesis and its role in fear memory modulation

Olfaction is a critical sense that allows animals to navigate and understand their environment. In mammals, the critical brain structure to receive and process olfactory information is the olfactory bulb, a structure characterized by a laminated pattern with different types of neurons, some of which...

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Autores principales: Silvas-Baltazar, Monserrat, López-Oropeza, Grecia, Durán, Pilar, Martínez-Canabal, Alonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569173/
https://www.ncbi.nlm.nih.gov/pubmed/37840547
http://dx.doi.org/10.3389/fnbeh.2023.1278324
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author Silvas-Baltazar, Monserrat
López-Oropeza, Grecia
Durán, Pilar
Martínez-Canabal, Alonso
author_facet Silvas-Baltazar, Monserrat
López-Oropeza, Grecia
Durán, Pilar
Martínez-Canabal, Alonso
author_sort Silvas-Baltazar, Monserrat
collection PubMed
description Olfaction is a critical sense that allows animals to navigate and understand their environment. In mammals, the critical brain structure to receive and process olfactory information is the olfactory bulb, a structure characterized by a laminated pattern with different types of neurons, some of which project to distant telencephalic structures, like the piriform cortex, the amygdala, and the hippocampal formation. Therefore, the olfactory bulb is the first structure of a complex cognitive network that relates olfaction to different types of memory, including episodic memories. The olfactory bulb continuously adds inhibitory newborn neurons throughout life; these cells locate both in the granule and glomerular layers and integrate into the olfactory circuits, inhibiting projection neurons. However, the roles of these cells modulating olfactory memories are unclear, particularly their role in fear memories. We consider that olfactory neurogenesis might modulate olfactory fear memories by a plastic process occurring in the olfactory bulb.
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spelling pubmed-105691732023-10-13 Olfactory neurogenesis and its role in fear memory modulation Silvas-Baltazar, Monserrat López-Oropeza, Grecia Durán, Pilar Martínez-Canabal, Alonso Front Behav Neurosci Behavioral Neuroscience Olfaction is a critical sense that allows animals to navigate and understand their environment. In mammals, the critical brain structure to receive and process olfactory information is the olfactory bulb, a structure characterized by a laminated pattern with different types of neurons, some of which project to distant telencephalic structures, like the piriform cortex, the amygdala, and the hippocampal formation. Therefore, the olfactory bulb is the first structure of a complex cognitive network that relates olfaction to different types of memory, including episodic memories. The olfactory bulb continuously adds inhibitory newborn neurons throughout life; these cells locate both in the granule and glomerular layers and integrate into the olfactory circuits, inhibiting projection neurons. However, the roles of these cells modulating olfactory memories are unclear, particularly their role in fear memories. We consider that olfactory neurogenesis might modulate olfactory fear memories by a plastic process occurring in the olfactory bulb. Frontiers Media S.A. 2023-09-28 /pmc/articles/PMC10569173/ /pubmed/37840547 http://dx.doi.org/10.3389/fnbeh.2023.1278324 Text en Copyright © 2023 Silvas-Baltazar, López-Oropeza, Durán and Martínez-Canabal. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Behavioral Neuroscience
Silvas-Baltazar, Monserrat
López-Oropeza, Grecia
Durán, Pilar
Martínez-Canabal, Alonso
Olfactory neurogenesis and its role in fear memory modulation
title Olfactory neurogenesis and its role in fear memory modulation
title_full Olfactory neurogenesis and its role in fear memory modulation
title_fullStr Olfactory neurogenesis and its role in fear memory modulation
title_full_unstemmed Olfactory neurogenesis and its role in fear memory modulation
title_short Olfactory neurogenesis and its role in fear memory modulation
title_sort olfactory neurogenesis and its role in fear memory modulation
topic Behavioral Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10569173/
https://www.ncbi.nlm.nih.gov/pubmed/37840547
http://dx.doi.org/10.3389/fnbeh.2023.1278324
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